Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 20/20 | 0.68 |
| ▸ | SCN5A | Q14524 | 20/20 | 0.68 |
| ▸ | SCN8A | Q9UQD0 | 20/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20256523 | 0.89 | SCN1A (0.68) | SCN1ASCN5ASCN8A | |
| SCHEMBL20256484 | 0.86 | SCN5A (0.48) | SCN1ASCN5ASCN8A | |
| SCHEMBL20256541 | 0.86 | SCN5A (0.48) | SCN1ASCN5ASCN8A | |
| SCHEMBL20256498 | 0.84 | SCN1A (0.68) | SCN1ASCN5ASCN8ANR1I2SCN1B | |
| SCHEMBL20256532 | 0.84 | SCN8A (0.69) | SCN1ASCN5ASCN8ANR1I2SCN1B | |
| SCHEMBL20237574 | 0.81 | SCN5A (1.00) | SCN1ASCN5ASCN8ANR1I2SCN1B | |
| SCHEMBL29669016 | 0.81 | SCN5A (1.00) | SCN1ASCN5ASCN8ANR1I2SCN1B | |
| SCHEMBL20256668 | 0.80 | SCN5A (0.69) | SCN1ASCN5ASCN8ANR1I2SCN1B | |
| SCHEMBL20256355 | 0.80 | SCN1A (0.70) | SCN1ASCN5ASCN8ANR1I2SCN1B | |
| SCHEMBL20256912 | 0.80 | SCN1A (0.67) | SCN1ASCN5ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106284-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2018-06-14 | — | — | WO | disclosed |