Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | DHPS | P49366 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20257083 | 0.99 | CYP11B1 (0.40) | CYP11B1CYP11B2MAPK14PIK3CACYP17A1 | |
| SCHEMBL20257073 | 0.98 | CYP11B1 (0.41) | CYP11B1CYP11B2MAPK14PIK3CACYP17A1 | |
| SCHEMBL20256994 | 0.97 | CYP11B1 (0.41) | CYP11B1CYP11B2MAPK14PIK3CACYP17A1 | |
| SCHEMBL17012241 | 0.88 | CYP1A2 (0.41) | CYP11B1CYP11B2MAPK14PIK3CACYP1A2 | |
| SCHEMBL29291490 | 0.86 | CYP11B2 (0.38) | CYP11B1CYP11B2MAPK14PIK3CACYP17A1 | |
| SCHEMBL16485274 | 0.85 | CYP1A2 (0.42) | CYP11B1CYP11B2MAPK14CYP1A2ROCK1 | |
| SCHEMBL20256995 | 0.84 | CYP11B1 (0.34) | CYP11B1CYP11B2MAPK14PIK3CACYP1A2 | |
| SCHEMBL29291492 | 0.83 | CYP11B1 (0.40) | CYP11B1CYP11B2MAPK14PIK3CACYP17A1 | |
| SCHEMBL8739891 | 0.83 | CYP11B2 (0.45) | CYP11B1CYP11B2PIK3CACYP17A1CYP19A1 | |
| SCHEMBL18697599 | 0.83 | CYP11B1 (0.51) | CYP11B1CYP11B2PIK3CACYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018103746-A1 | CARBAZOLE BENZENE FUSED RING DERIVATIVE, POLYMER, MIXTURE, COMPOSITION, ORGANIC ELECTRONIC DEVICE AND PREPARATION METHOD THEREFOR | 广州华睿光电材料有限公司 | 2018-06-14 | — | — | WO | disclosed |