Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19146437 | 0.79 | KMT2A (0.41) | TSHRPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20648739 | 0.76 | KMT2A (0.44) | TSHRPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22562932 | 0.76 | ALDH1A1 (0.32) | TSHRPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL18457392 | 0.71 | POLB (0.48) | TSHRPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14094290 | 0.70 | KMT2A (0.43) | TSHRPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19302551 | 0.69 | POLB (0.43) | TSHRPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL18868414 | 0.69 | KMT2A (0.40) | TSHRPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29319224 | 0.68 | KMT2A (0.42) | TSHRPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10292539 | 0.68 | LPAR3 (0.34) | — | |
| SCHEMBL30658494 | 0.68 | TSHR (0.43) | TSHRPOLBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106666-A1 | ORAL CARE COPOLYMERS AND COMPOSITIONS AND METHODS FOR USE | ISP INVESTMENTS LLC (US) | 2018-06-14 | — | — | WO | disclosed |