Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA4 | P22748 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19703937 | 0.87 | NPC1 (0.40) | MGLLHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29608026 | 0.85 | MGLL (0.55) | MGLLHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29441383 | 0.85 | MGLL (0.55) | MGLLHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29869052 | 0.85 | MGLL (0.55) | MGLLHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30259429 | 0.85 | MGLL (0.55) | MGLLHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL24621693 | 0.85 | MGLL (0.55) | MGLLHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29869032 | 0.85 | MGLL (0.55) | MGLLHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10018583 | 0.85 | MGLL (0.55) | MGLLHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL19698597 | 0.84 | P2RY14 (0.35) | MGLLSMN1; SMN2HPGDHTTKMT2A | |
| SCHEMBL20254026 | 0.84 | MGLL (0.47) | MGLLALDH1A1SMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836493-B1 | FUNCTIONALIZED THIENO-INDOLE DERIVATIVES FOR THE TREATMENT OF CANCER | NERVIANO MEDICAL SCIENCES SRL (IT) | 2018-06-20 | — | — | EP | claimed |