SCHEMBL20262467

SCHEMBL20262467

CCCOC(=O)C(=CC1CCC1)C(=O)OCCC

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.35
PPM1B O75688 1/20 0.35
PTPN1 P18031 1/20 0.35
PPP1CC P36873 1/20 0.35
ALDH1A1 P00352 1/20 0.34
NPSR1 Q6W5P4 1/20 0.32
GLO1 Q04760 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
GAA P10253 1/20 0.31
ADH1A P07327 2/20 0.31
ADH1C P00326 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
POLB P06746 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15913578 0.96 HCAR2 (0.35) HCAR2PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL15913355 0.95 HCAR2 (0.34) HCAR2PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL20262465 0.90 ATM (0.43) HCAR2ALDH1A1NPSR1SMN1; SMN2HPGD
SCHEMBL20601871 0.90 GRIK1 (0.37) HCAR2PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL15913701 0.86 ATM (0.43) HCAR2ALDH1A1HPGDTSHR
SCHEMBL20262516 0.85 NPSR1 (0.47) ALDH1A1NPSR1GLO1SMN1; SMN2GAA
SCHEMBL15914179 0.85 ATM (0.42) HCAR2ALDH1A1SMN1; SMN2TP53HPGD
SCHEMBL15913663 0.81 NPSR1 (0.47) ALDH1A1NPSR1GLO1SMN1; SMN2GAA
SCHEMBL15913874 0.81 PPM1B (0.33) HCAR2PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL28473155 0.81 HCAR2 (0.34) HCAR2PPM1BPTPN1PPP1CCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10308563-B2 Process for producing ethylene oligomers HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2019-06-04 US disclosed
CN-108212215-A The catalyst system closed for ethylene oligomerization and the method using its production ethylene low polymer 韩华道达尔有限公司 2018-06-29 CN disclosed
CN-108218652-A The method for producing ethylene low polymer 韩华道达尔有限公司 2018-06-29 CN disclosed
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US disclosed
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10308563-B2 Process for producing ethylene oligomers OXER1, HAO2, ORC3 HCAR2 159/4885PPM1B 4279/4885PTPN1 4333/4885
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HACL2, HAO2, MSMO1 HCAR2 212/4885PPM1B 4507/4885PTPN1 4589/4885
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS OXER1, HAO2, ORC3 HCAR2 159/4885PPM1B 4279/4885PTPN1 4333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.