Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.55 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528528 | 0.75 | CES1 (0.39) | GSK3BGSK3ABRCA1ALDH1A1MAPT | |
| SCHEMBL8938744 | 0.72 | GSK3B (0.45) | GSK3BGSK3ATSHRALDH1A1MAPT | |
| SCHEMBL10623745 | 0.72 | GSK3B (0.45) | GSK3BGSK3AALDH1A1MAPTMEN1 | |
| SCHEMBL28522247 | 0.72 | MAPT (0.57) | GSK3BALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL454828 | 0.71 | POLB (0.51) | GSK3BALDH1A1MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL15282882 | 0.71 | MAPT (0.55) | GSK3BALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28557252 | 0.70 | SRD5A1 (0.49) | GSK3BGSK3ASRD5A1ALOX15TSHR | |
| SCHEMBL17622326 | 0.70 | TSHR (0.55) | GSK3BGSK3ASRD5A1ALOX15TSHR | |
| SCHEMBL30999985 | 0.70 | GSK3B (0.81) | GSK3BGSK3ASRD5A1ALOX15TSHR | |
| SCHEMBL30999951 | 0.69 | GSK3B (1.00) | GSK3BGSK3ASRD5A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018108627-A1 | USE OF SUBSTITUTED INDOLINYLMETHYL SULFONAMIDES, OR THE SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE OF PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-21 | — | — | WO | disclosed |