⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20267487 | 0.79 | — | — | |
| SCHEMBL11030675 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL20267889 | 0.70 | — | — | |
| SCHEMBL20267857 | 0.62 | — | — | |
| SCHEMBL5081420 | 0.60 | — | — | |
| SCHEMBL17504550 | 0.57 | — | — | |
| SCHEMBL975641 | 0.56 | — | — | |
| SCHEMBL15671221 | 0.56 | — | — | |
| SCHEMBL8137903 | 0.56 | — | — | |
| SCHEMBL35604 | 0.53 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3554559-A1 | METHOD FOR LABELING OF SENSITIVE AND THERMOSENSITIVE TARGETING BIOMOLECULES WITH TECHNETIUM BASED COMPOUNDS | Bracco Imaging SpA (IT) | 2019-10-23 | — | — | EP | claimed |
| WO-2018109164-A1 | METHOD FOR LABELING OF SENSITIVE AND THERMOSENSITIVE TARGETING BIOMOLECULES WITH TECHNETIUM BASED COMPOUNDS | BRACCO IMAGING SPA (IT) | 2018-06-21 | — | — | WO | claimed |
| US-20220054663-A1 | METHOD FOR LABELING OF SENSITIVE AND THERMOSENSITIVE TARGETING BIOMOLECULES WITH TECHNETIUM BASED COMPOUNDS | BRACCO IMAGING SPA (IT) | 2022-02-24 | — | — | US | disclosed |
| EP-3554559-B1 | METHOD FOR LABELING OF SENSITIVE AND THERMOSENSITIVE TARGETING BIOMOLECULES WITH TECHNETIUM BASED COMPOUNDS | BRACCO IMAGING SPA (IT) | 2022-02-02 | — | — | EP | disclosed |
| US-11160886-B2 | Method for labeling of sensitive and thermosensitive targeting biomolecules with technetium based compounds | BRACCO IMAGING SPA (IT) | 2021-11-02 | — | — | US | disclosed |
| US-20200078479-A1 | METHOD FOR LABELING OF SENSITIVE AND THERMOSENSITIVE TARGETING BIOMOLECULES WITH TECHNETIUM BASED COMPOUNDS | BRACCO IMAGING SPA (IT) | 2020-03-12 | — | — | US | disclosed |
| EP-3554559-A1 | METHOD FOR LABELING OF SENSITIVE AND THERMOSENSITIVE TARGETING BIOMOLECULES WITH TECHNETIUM BASED COMPOUNDS | Bracco Imaging SpA (IT) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018109164-A1 | METHOD FOR LABELING OF SENSITIVE AND THERMOSENSITIVE TARGETING BIOMOLECULES WITH TECHNETIUM BASED COMPOUNDS | BRACCO IMAGING SPA (IT) | 2018-06-21 | — | — | WO | disclosed |