Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15750188 | 0.91 | HRH3 (0.49) | HRH3LTA4HHRH4ABCB1DRD2 | |
| SCHEMBL20274150 | 0.82 | HRH3 (0.68) | HRH3LTA4HHRH4 | |
| SCHEMBL20274171 | 0.82 | HRH3 (0.49) | HRH3LTA4HHRH4 | |
| SCHEMBL20274114 | 0.82 | HRH3 (0.56) | HRH3LTA4HHRH4 | |
| SCHEMBL15707813 | 0.81 | HRH3 (0.51) | HRH3LTA4HHRH4ABCB1DRD2 | |
| SCHEMBL20274110 | 0.79 | HRH3 (0.60) | HRH3LTA4HHRH4ABCB1 | |
| SCHEMBL20274162 | 0.78 | HRH3 (0.49) | HRH3LTA4HHRH4ABCB1DRD2 | |
| SCHEMBL20274126 | 0.75 | HRH3 (0.44) | HRH3LTA4HHRH4ABCB1DRD2 | |
| SCHEMBL15749956 | 0.73 | MEN1 (0.52) | HRH3LTA4HHRH4 | |
| SCHEMBL15708224 | 0.73 | HRH3 (0.68) | HRH3LTA4HHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |