Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15750188 | 0.86 | HRH3 (0.49) | HRH3HRH4ABCB1DRD2LTA4H | |
| SCHEMBL15707813 | 0.81 | HRH3 (0.51) | HRH3HRH4ABCB1DRD2LTA4H | |
| SCHEMBL20274145 | 0.78 | HRH3 (0.56) | HRH3HRH4ABCB1DRD2LTA4H | |
| SCHEMBL15707823 | 0.78 | HRH3 (0.67) | HRH3HRH4ABCB1DRD2SIGMAR1 | |
| SCHEMBL8020106 | 0.76 | SIGMAR1 (0.59) | HRH3HRH4ABCB1DRD2HTR1A | |
| SCHEMBL20274126 | 0.74 | HRH3 (0.44) | HRH3HRH4ABCB1DRD2LTA4H | |
| SCHEMBL9377623 | 0.74 | HRH3 (0.43) | HRH3HRH4DRD2HTR1AADRA2A | |
| SCHEMBL15740462 | 0.73 | HRH3 (0.50) | HRH3HRH4ABCB1DRD2HTR1A | |
| SCHEMBL20274150 | 0.72 | HRH3 (0.68) | HRH3HRH4LTA4HADRA2ACHRM1 | |
| SCHEMBL20274171 | 0.72 | HRH3 (0.49) | HRH3HRH4LTA4HHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |