Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25373812 | 0.88 | YTHDC1 (0.44) | YTHDC1ALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL25373818 | 0.88 | YTHDC1 (0.44) | YTHDC1ALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL17802169 | 0.83 | YTHDC1 (0.44) | SLC6A2SLC6A4MEN1KMT2AYTHDC1 | |
| SCHEMBL17802168 | 0.83 | YTHDC1 (0.44) | SLC6A2SLC6A4MEN1KMT2AYTHDC1 | |
| SCHEMBL17802181 | 0.81 | YTHDC1 (0.47) | SLC6A2SLC6A4MEN1KMT2AYTHDC1 | |
| SCHEMBL19328314 | 0.81 | YTHDC1 (0.47) | SLC6A2SLC6A4MEN1KMT2AYTHDC1 | |
| SCHEMBL15740441 | 0.81 | YTHDC1 (0.49) | SLC6A2SLC6A4MEN1KMT2AYTHDC1 | |
| SCHEMBL8894747 | 0.81 | YTHDC1 (0.49) | SLC6A2SLC6A4MEN1KMT2AYTHDC1 | |
| SCHEMBL15707864 | 0.81 | AKT1 (0.43) | SLC6A2SLC6A4MEN1KMT2AYTHDC1 | |
| SCHEMBL24126275 | 0.81 | AKT1 (0.43) | SLC6A2SLC6A4MEN1KMT2AYTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |