Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9281840 | 0.83 | MEN1 (0.38) | APPMEN1KMT2ATSHRALOX15 | |
| SCHEMBL11214926 | 0.82 | SMN1; SMN2 (0.46) | APPMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL27717723 | 0.82 | ALDH1A1 (0.52) | APPMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL27049050 | 0.81 | SMN1; SMN2 (0.41) | MEN1KMT2ATSHRALOX15MAPK1 | |
| SCHEMBL13127247 | 0.81 | PDE3B (0.52) | APPMEN1KMT2ATSHRALOX15 | |
| Hydrochloric Acid SCHEMBL1842062 | 0.80 | ALDH1A1 (0.55) | APPMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL16564658 | 0.80 | PDE3B (0.44) | APPMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL9229437 | 0.79 | APP (0.49) | APPMEN1KMT2ATSHRALOX15 | |
| SCHEMBL26444101 | 0.79 | MEN1 (0.58) | APPMEN1KMT2ATSHRALOX15 | |
| SCHEMBL18509237 | 0.79 | PDE3B (0.45) | APPMEN1KMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-A1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial Inc. (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |