Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.56 |
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124461 | 0.81 | RAB9A (0.71) | RAB9ANPC1DAOALDH1A1HPGD | |
| SCHEMBL12124462 | 0.79 | RAB9A (0.73) | RAB9ANPC1ALDH1A1HPGDKMT2A | |
| SCHEMBL12124368 | 0.77 | RAB9A (0.67) | RAB9ANPC1DAOALDH1A1HPGD | |
| SCHEMBL20925996 | 0.75 | HTT (0.44) | RAB9ANPC1ALDH1A1HPGDKMT2A | |
| SCHEMBL12124434 | 0.73 | NPC1 (0.62) | RAB9ANPC1DAOALDH1A1HPGD | |
| SCHEMBL22279371 | 0.71 | NPC1 (0.66) | RAB9ANPC1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL22055783 | 0.69 | NPC1 (0.44) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22877114 | 0.68 | RAB9A (0.53) | RAB9ANPC1ALDH1A1HPGDKMT2A | |
| SCHEMBL12124244 | 0.68 | KDM1A (0.56) | RAB9ANPC1DAOALDH1A1HPGD | |
| SCHEMBL12124258 | 0.68 | NPC1 (0.55) | RAB9ANPC1DAOALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3336090-B1 | IRAK4 INHIBITOR AND USE THEREOF | BEIJING HANMI PHARMACEUTICAL CO LTD (CN) | 2020-07-22 | — | — | EP | disclosed |
| EP-3336090-A1 | IRAK4 INHIBITOR AND USE THEREOF | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2018-06-20 | — | — | EP | disclosed |