Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.35 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 6/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27471326 | 0.93 | TSHR (0.35) | TSHR | |
| SCHEMBL2029412 | 0.74 | APOBEC3A (0.37) | TSHRPPARGPDIA3PDIA6NFKB1 | |
| SCHEMBL2029410 | 0.74 | APOBEC3A (0.37) | TSHRPPARGPDIA3PDIA6NFKB1 | |
| SCHEMBL5423344 | 0.73 | TSHR (0.41) | TSHRPPARGPDIA3PDIA6TYR | |
| SCHEMBL24740595 | 0.72 | PRKCA (0.38) | TSHRPPARGPDIA3PDIA6TYR | |
| SCHEMBL9063670 | 0.70 | — | — | |
| SCHEMBL1797486 | 0.67 | TSHR (0.44) | TSHRPPARGNFKB1NFKB2RELA | |
| SCHEMBL21300 | 0.67 | TSHR (0.44) | TSHRPPARGNFKB1NFKB2RELA | |
| SCHEMBL14915686 | 0.67 | TSHR (0.44) | TSHRPPARGNFKB1NFKB2RELA | |
| SCHEMBL15618662 | 0.67 | TSHR (0.44) | TSHRPPARGNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513082-B1 | New dioxalane and dioxane derivatives and method for producing same | BAYER CROPSCIENCE AG (DE) | 2013-10-02 | — | — | EP | claimed |
| CN-102656155-B | Dioxolane and dioxane derivatives and process for preparing same | BAYER CROPSCIENCE AG | 2015-01-14 | — | — | CN | disclosed |
| EP-2513082-A1 | NOVEL DIOXOLANE AND DIOXANE DERIVATIVES, AND A METHOD FOR THE PRODUCTION THEREOF | Bayer CropScience AG (DE) | 2012-10-24 | — | — | EP | disclosed |
| CN-102656155-A | Novel dioxolane and dioxane derivatives and process for their preparation | BAYER CROPSCIENCE AG | 2012-09-05 | — | — | CN | disclosed |
| US-8222435-B2 | Dioxolane and dioxane derivatives and a process for their preparation | BAYER CROPSCIENCE AG (DE) | 2012-07-17 | — | — | US | disclosed |
| US-8222435-B2 | Dioxolane and dioxane derivatives and a process for their preparation | BAYER CROPSCIENCE AG (DE) | 2012-07-17 | — | — | US | disclosed |
| US-20110152531-A1 | Novel Dioxolane And Dioxane Derivatives And A Process For Their Preparation | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| US-20110152531-A1 | Novel Dioxolane And Dioxane Derivatives And A Process For Their Preparation | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| WO-2011073100-A1 | NOVEL DIOXOLANE AND DIOXANE DERIVATIVES, AND A METHOD FOR THE PRODUCTION THEREOF | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152531-A1 | Novel Dioxolane And Dioxane Derivatives And A Process For Their Preparation | ACOX1, CYP4X1, ANTXR2 | TSHR 1572/4885PPARG 2495/4885PDIA3 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.