Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668755 | 0.98 | RECQL (0.46) | RECQLCYP3A4TSHRTDP1ATM | |
| Potassium Ion SCHEMBL11852844 | 0.98 | RECQL (0.46) | RECQLCYP3A4TSHRTDP1ATM | |
| SCHEMBL910051 | 0.88 | RECQL (0.48) | RECQLCYP3A4TSHRTDP1ATM | |
| SCHEMBL11140325 | 0.87 | RECQL (0.47) | RECQLCYP3A4TSHRTDP1ATM | |
| Silver SCHEMBL5574910 | 0.85 | CA2 (0.46) | RECQLCYP3A4TSHRTDP1ATM | |
| SCHEMBL2206851 | 0.85 | RECQL (0.35) | RECQLCYP3A4TSHRTDP1ATM | |
| Potassium Ion SCHEMBL816755 | 0.82 | CA2 (0.46) | RECQLCYP3A4TSHRTDP1ATM | |
| SCHEMBL6230350 | 0.82 | CA2 (0.49) | RECQLCYP3A4TSHRTDP1ATM | |
| Lithium Ion SCHEMBL21747203 | 0.82 | CA2 (0.46) | RECQLCYP3A4TSHRTDP1ATM | |
| SCHEMBL818559 | 0.82 | CA2 (0.49) | RECQLCYP3A4TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696515-B1 | Ink jet printing process | AGFA GEVAERT NV (BE) | 1998-12-02 | — | — | EP | claimed |
| EP-0697282-B1 | Process for the prodcution of a printing plate by inkjet | AGFA GEVAERT NV (BE) | 1998-12-02 | — | — | EP | claimed |
| US-5751325-A | WORKING RELATIONSHIP OF A REDUCING AGENT FOR A METAL COMPOUNDAND PHYSICAL NUCLEI THAT CATALYZE THE METAL | AGFA-GEVAERT, N.V. (BE) | 1998-05-12 | — | — | US | claimed |
| US-5501150-A | Process for the production of a printing plate by inkjet | AGFA-GEVAERT, N.V. (BE) | 1996-03-26 | — | — | US | claimed |
| EP-0697282-A1 | Process for the prodcution of a printing plate by inkjet | AGFA-GEVAERT N.V. (BE) | 1996-02-21 | — | — | EP | claimed |
| EP-0696515-A1 | Ink jet printing process | AGFA-GEVAERT N.V. (BE) | 1996-02-14 | — | — | EP | claimed |
| US-6436625-B1 | — | — | None | — | — | US | disclosed |
| US-20120241693-A1 | AQUEOUS-BASED DISPERSIONS OF METAL NANOPARTICLES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2012-09-27 | — | — | US | disclosed |
| US-8227022-B2 | Method of forming aqueous-based dispersions of metal nanoparticles | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2012-07-24 | — | — | US | disclosed |
| US-7963646-B2 | Ink-jet inks containing metal nanoparticles | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM ISRAELL COMPANY (IL) | 2011-06-21 | — | — | US | disclosed |
| EP-1853673-B1 | AQUEOUS-BASED DISPERSIONS OF METAL NANOPARTICLES | YISSUM RES DEV CO (IL) | 2010-03-24 | — | — | EP | disclosed |
| US-20090214766-A1 | AQUEOUS-BASED DISPERSIONS OF METAL NANOPARTICLES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2009-08-27 | — | — | US | disclosed |
| EP-0922994-B1 | A photosensitive silver halide element with increased photosensitivity | CENTRE NAT RECH SCIENT (FR) | 2009-08-19 | — | — | EP | disclosed |
| EP-0663301-A1 | Recording material for a direct thermal imaging process | AGFA-GEVAERT N.V. (BE) | 1995-07-19 | — | — | EP | disclosed |
| WO-1995012495-A1 | DIRECT THERMAL IMAGING METHOD USING A PROTECTED HEAT-SENSITIVE RECORDING MATERIAL | AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) | 1995-05-11 | — | — | WO | disclosed |
| EP-0641670-A1 | Ink jet printing method | AGFA-GEVAERT N.V. (BE) | 1995-03-08 | — | — | EP | disclosed |
| EP-0641669-A1 | Ink jet recording method operating with a chemically reactive ink | AGFA-GEVAERT N.V. (BE) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994011199-A1 | DIRECT THERMAL IMAGING MATERIAL | AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) | 1994-05-26 | — | — | WO | disclosed |
| WO-1994011198-A1 | DIRECT THERMAL IMAGING MATERIAL | AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) | 1994-05-26 | — | — | WO | disclosed |
| EP-0227141-A1 | A process for the production of a photothermographic material | AGFA-GEVAERT N.V. (BE) | 1987-07-01 | — | — | EP | disclosed |