Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20280488 | 0.98 | MEN1 (0.34) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL20288337 | 0.92 | MEN1 (0.39) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL20267798 | 0.92 | MEN1 (0.35) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL20267791 | 0.91 | MAPT (0.36) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL20268996 | 0.91 | MEN1 (0.40) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL20280302 | 0.90 | — | — | |
| SCHEMBL20280498 | 0.89 | MEN1 (0.30) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL22102729 | 0.88 | MAPT (0.36) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL22701347 | 0.87 | MEN1 (0.32) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL20280682 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555069-B1 | NOVEL AZOMETHINE DIRECT DYES BEARING AT LEAST ONE CATIONIC CHARGE, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | OREAL (FR) | 2022-03-30 | — | — | EP | disclosed |
| WO-2018109192-A1 | NOVEL AZOMETHINE DIRECT DYES BEARING AT LEAST ONE CATIONIC CHARGE, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | L'OREAL (FR) | 2018-06-21 | — | — | WO | disclosed |