SCHEMBL20280682

SCHEMBL20280682

C[n+]1ccn(CCCNc2ccc(Nc3cc(Nc4ccc(N5CCC([N+](C)(C)C)C5)cc4)c(N)cc3O)cc2)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20280485 0.84 MEN1 (0.35)
SCHEMBL20280488 0.83 MEN1 (0.34)
SCHEMBL20280612 0.82 SYK (0.32)
SCHEMBL24348970 0.79 QPCT (0.33)
SCHEMBL20288337 0.78 MEN1 (0.39)
SCHEMBL20267798 0.77 MEN1 (0.35)
SCHEMBL20267791 0.77 MAPT (0.36)
SCHEMBL20268996 0.77 MEN1 (0.40)
SCHEMBL20280384 0.76
SCHEMBL29423414 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3555069-B1 NOVEL AZOMETHINE DIRECT DYES BEARING AT LEAST ONE CATIONIC CHARGE, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF OREAL (FR) 2022-03-30 EP disclosed
WO-2018109192-A1 NOVEL AZOMETHINE DIRECT DYES BEARING AT LEAST ONE CATIONIC CHARGE, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF L'OREAL (FR) 2018-06-21 WO disclosed