Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21618614 | 0.95 | TSHR (0.46) | TSHRPOLBL3MBTL1PRMT5WDR77 | |
| SCHEMBL20280886 | 0.92 | TSHR (0.47) | TSHRPOLBL3MBTL1PRMT5WDR77 | |
| SCHEMBL20281042 | 0.87 | TSHR (0.43) | TSHRPOLBL3MBTL1PRMT5WDR77 | |
| SCHEMBL20281026 | 0.87 | TSHR (0.43) | TSHRPOLBL3MBTL1PRMT5WDR77 | |
| SCHEMBL20280975 | 0.86 | ALDH1A1 (0.36) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL20281066 | 0.85 | ALDH1A1 (0.42) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21618644 | 0.81 | TSHR (0.46) | TSHRPOLBL3MBTL1PRMT5WDR77 | |
| SCHEMBL21618604 | 0.81 | TSHR (0.46) | TSHRPOLBL3MBTL1PRMT5WDR77 | |
| SCHEMBL21618567 | 0.80 | ALDH1A1 (0.35) | POLBALDH1A1KDM4EUSP2ALOX15 | |
| SCHEMBL20281069 | 0.79 | ALDH1A1 (0.46) | TSHRPOLBL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018108780-A1 | DIMERIC CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2018-06-21 | — | — | WO | disclosed |