Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 3/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19604915 | 0.78 | HRH3 (0.45) | KCNH2MCHR1HRH3HRH4 | |
| SCHEMBL20283148 | 0.76 | GRM4 (0.46) | KCNH2MCHR1HRH3CNR2HRH4 | |
| SCHEMBL23046561 | 0.76 | GRM1 (0.44) | KCNH2MCHR1HRH3HRH4 | |
| SCHEMBL23775243 | 0.73 | HRH4 (0.50) | HRH3HRH4 | |
| SCHEMBL26581344 | 0.72 | ACACB (0.51) | HRH3RETHRH4 | |
| SCHEMBL2636592 | 0.67 | HRH4 (0.55) | KCNH2MCHR1HRH3HRH4 | |
| SCHEMBL12344779 | 0.67 | HRH4 (0.52) | KCNH2MCHR1HRH3HRH4 | |
| SCHEMBL1778455 | 0.66 | HRH4 (0.51) | KCNH2MCHR1HRH3HRH4 | |
| SCHEMBL14372885 | 0.66 | HRH4 (0.51) | KCNH2MCHR1HRH3HRH4 | |
| SCHEMBL13506774 | 0.66 | HRH3 (0.57) | HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018112312-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY (US) | 2018-06-21 | — | — | WO | disclosed |