SCHEMBL20284142

SCHEMBL20284142

CCCCc1nc2c(N)nc3ccccc3c2n1CCCCNC(=O)C1CCC(C)CC1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.62
TLR8 Q9NR97 8/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20283949 0.94 TLR7 (0.64) TLR7TLR8
SCHEMBL24860125 0.91 TLR7 (0.60) TLR7TLR8
SCHEMBL24860092 0.90 TLR7 (0.59) TLR7TLR8
SCHEMBL20284122 0.89 TLR7 (0.56) TLR7TLR8
SCHEMBL20647729 0.88 TLR7 (0.56) TLR7TLR8
SCHEMBL20801394 0.88 TLR7 (0.57) TLR7TLR8
SCHEMBL20801395 0.88 TLR7 (0.57) TLR7TLR8
SCHEMBL24860024 0.88 TLR7 (0.57) TLR7TLR8
SCHEMBL30488613 0.88 TLR7 (0.57) TLR7TLR8
SCHEMBL22181054 0.86 TLR7 (0.59) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018112108-A1 ANTIBODY ADJUVANT CONJUGATES BOLT BIOTHERAPEUTICS, INC. (US) 2018-06-21 WO disclosed