SCHEMBL20801394

SCHEMBL20801394

CCCCc1nc2c(N)nc3ccccc3c2n1CCCCNC(=O)[C@H]1CC[C@H](CN2C(=O)C=CC2=O)CC1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.57
TLR8 Q9NR97 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24860024 1.00 TLR7 (0.57) TLR7TLR8
SCHEMBL20801395 1.00 TLR7 (0.57) TLR7TLR8
SCHEMBL30488613 1.00 TLR7 (0.57) TLR7TLR8
SCHEMBL22062027 0.92 TLR7 (0.56) TLR7TLR8
SCHEMBL24860124 0.89 TLR7 (0.53) TLR7TLR8
SCHEMBL20283949 0.88 TLR7 (0.64) TLR7TLR8
SCHEMBL20284142 0.88 TLR7 (0.62) TLR7TLR8
SCHEMBL20801449 0.86 TLR7 (0.49) TLR7TLR8
SCHEMBL22181062 0.86 TLR7 (0.49) TLR7TLR8
SCHEMBL22181004 0.86 TLR7 (0.49) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023170608-A1 ACTIVATORS OF EFFECTOR T CELLS ORUM THERAPEUTICS, INC. (KR) 2023-09-14 WO disclosed
US-11547761-B1 Antibody adjuvant conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-01-10 US disclosed
US-20210284750-A1 Immunoconjugate Synthesis Method BOLT BIOTHERAPEUTICS, INC. (US) 2021-09-16 US disclosed
US-11110178-B2 Antibody adjuvant conjugates THE BOARD OF TRUSTEES OF THE LELAND STANDFORD JUNIOR UNIVERSITY (US) 2021-09-07 US disclosed
US-20200206357-A1 ANTIBODY ADJUVANT CONJUGATES BOLT BIOTHERAPEUTICS, INC. 2020-07-02 US disclosed
US-10675358-B2 Antibody adjuvant conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2020-06-09 US disclosed
US-20190076547-A1 ANTIBODY ADJUVANT CONJUGATES BOLT BIOTHERAPEUTICS, INC. 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200206357-A1 ANTIBODY ADJUVANT CONJUGATES FCGR1A, FCGR3B, FCGR2A TLR7 58/4885TLR8 56/4885
US-10675358-B2 Antibody adjuvant conjugates FCGR1A, FCGR3B, FCGR2A TLR7 58/4885TLR8 56/4885
US-20190076547-A1 ANTIBODY ADJUVANT CONJUGATES FCGR1A, FCGR3B, FCGR2A TLR7 57/4885TLR8 59/4885
US-20210284750-A1 Immunoconjugate Synthesis Method FCGR3B, FCGR1A, FCGR2A TLR7 84/4885TLR8 435/4885
US-11547761-B1 Antibody adjuvant conjugates FCGR1A, FCGR3B, FCGR2A TLR7 58/4885TLR8 56/4885
US-11110178-B2 Antibody adjuvant conjugates FCGR1A, FCGR3B, FCGR2A TLR7 58/4885TLR8 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.