Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 5/20 | 0.54 |
| ▸ | CES2 | O00748 | 4/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL2036300 | 1.00 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL7632557 | 1.00 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL4287422 | 1.00 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL31118434 | 1.00 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28610 | 1.00 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL8002876 | 0.98 | TSHR (0.61) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL27575474 | 0.94 | TSHR (0.56) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL10941362 | 0.94 | TSHR (0.56) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL17557412 | 0.94 | TSHR (0.56) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL10939111 | 0.91 | TSHR (0.60) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473752-B | Resin composition and use thereof | 日本瑞翁株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-117445376-A | Method for manufacturing polarizing plate | 日本瑞翁株式会社 | 2024-01-26 | — | — | CN | disclosed |
| US-10865302-B2 | Resin composition and use thereof | ZEON CORPORATION (JP) | 2020-12-15 | — | — | US | disclosed |
| US-20190040249-A1 | RESIN COMPOSITION AND USE THEREOF | ZEON CORPORATION (JP) | 2019-02-07 | — | — | US | disclosed |
| US-7968019-B2 | Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display | KONICA MINOLTA OPTO, INC. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7815823-B2 | Optical film, manufacturing method of optical film, optical compensating film, manufacturing method of optical compensating film, polarizing plate, and liquid crystal display | KONICA MINOLTA OPTO, INC. (JP) | 2010-10-19 | — | — | US | disclosed |
| US-20090316084-A1 | Method of Producing Polarizing Plate, Polarizing Plate, and Liquid Crystal Display | KONICA MINOLTA OPTO, INC. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090286098-A1 | Optical Film, Method of Producing the Same and Image Displaying Apparatus Employing the Optical Film | KONICA MINOLTA OPTO, INC. (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090135345-A1 | Polarizing Plate Protective Film, Film Producing Method, Polarizing Plate, and Liquid Crystal Display | KONICA MINOLTA OPTO, INC. (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20060216437-A1 | Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display | KONICA MINOLTA OPTO, INC. (JP) | 2006-09-28 | — | — | US | disclosed |
| US-20060202366-A1 | Optical film, manufacturing method of optical film, optical compensating film, manufacturing method of optical compensating film, polarizing plate, and liquid crystal display | KONICA MINOLTA OPTO, INC. | 2006-09-14 | — | — | US | disclosed |
| US-20060078754-A1 | Optical film, polarizing plate and display | KONICA MINOLTA OPTO, INC. (JP) | 2006-04-13 | — | — | US | disclosed |