Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 5/20 | 0.54 |
| ▸ | CES2 | O00748 | 4/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL2036300 | 1.00 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL7632557 | 1.00 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL4287422 | 1.00 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2028573 | 1.00 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL31118434 | 1.00 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL8002876 | 0.98 | TSHR (0.61) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL27575474 | 0.94 | TSHR (0.56) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL10941362 | 0.94 | TSHR (0.56) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL17557412 | 0.94 | TSHR (0.56) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL10939111 | 0.91 | TSHR (0.60) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1046 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12390971-B2 | Process and system for blending a plasticizer with a polysaccharide ester polymer | CELANESE INTERNATIONAL CORPORATION (US) | 2025-08-19 | — | — | US | claimed |
| EP-4558557-A1 | COMPOSITION CONTAINING CELLULOSE ESTER POLYMER WITH ENHANCED MELT STRENGTH AGENT | Celanese International Corporation (US) | 2025-05-28 | — | — | EP | claimed |
| CN-119144262-B | Modified polyester hot melt adhesive and preparation process thereof | 深圳市东升塑胶制品有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119894971-A | Compositions containing cellulose ester polymers and enhanced melt strength agents | 国际人造丝公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119529424-A | Insulating plastic material | 惠州市万绿塑胶制品有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119144262-A | Modified polyester hot melt adhesive and preparation process thereof | 深圳市东升塑胶制品有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-119019955-A | Degradable hot melt adhesive and preparation process thereof | 深圳市东升塑胶制品有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-115112456-B | Method for preparing liquid-based cell slice | 山西尚宁高科技医学检验中心(有限公司) | 2024-11-22 | — | — | CN | claimed |
| CN-118909351-A | Fireproof PP (Polypropylene) recycling material for new energy and preparation method thereof | 东莞市宇捷实业投资有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-118440471-A | Scratch-resistant wear-resistant matte thermoplastic polyether ester elastomer rubber coating composition and preparation method thereof | 会通新材料(上海)有限公司 | 2024-08-06 | — | — | CN | claimed |
| US-5527616-A | CROSSLINKED POLYESTERURETHANE COPOLYMER HOT MELT ADHESIVE | TOYO SEIKAN KAISHA LTD. (JP) | 1996-06-18 | — | — | US | claimed |
| CN-1123738-A | Flexible powder-free vinyl gloves | EASTMAN CHEM CO (US) | 1996-06-05 | — | — | CN | claimed |
| US-5256717-A | Blends of butylene-ethylene copolymer and benzoate plasticizer | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1993-10-26 | — | — | US | claimed |
| EP-0161118-B1 | FLEXIBLE POLYVINYLIDENE FLUORIDE COMPOSITIONS, AND THEIR USE, ESPECIALLY IN MAKING FLEXIBLE TUBES | Institut Français du Pétrole (FR) | 1988-09-14 | — | — | EP | claimed |
| US-4584215-A | INCORPORATING ESTER IN POLYMER COMPOSITION | INSTITUT FRANCAIS DU PETROLE (FR) | 1986-04-22 | — | — | US | claimed |
| US-4382264-A | Magnetic imaging transfer process | XEROX CORPORATION (US) | 1983-05-03 | — | — | US | claimed |
| US-4304808-A | HEAT SENSITIVE COMPRISING METAL, ACRYLIC HOT MELT ADHESIVE, PLASTICIZER AND SOLVENT; DECALCOMANIA | JOHNSON, MATTHEY & CO., LIMITED (GB) | 1981-12-08 | — | — | US | claimed |
| US-4259225-A | STORAGE STABILITY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1981-03-31 | — | — | US | claimed |
| US-4172824-A | PLASTICIZER | EASTMAN KODAK COMPANY (US) | 1979-10-30 | — | — | US | claimed |
| US-4018728-A | PIGMENTARY MATERIALS, HOT MELT ADHESIVES, PLASTICIZER AND SOLVENT | JOHNSON MATTHEY & CO., LIMITED (EN) | 1977-04-19 | — | — | US | claimed |