⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL2026236 | 0.88 | PGK1 (0.31) | — | |
| SCHEMBL6620138 | 0.78 | — | — | |
| SCHEMBL19687235 | 0.78 | — | — | |
| SCHEMBL25707783 | 0.78 | — | — | |
| SCHEMBL17785870 | 0.78 | — | — | |
| SCHEMBL10438305 | 0.78 | HRH3 (0.38) | — | |
| Hydrochloric Acid SCHEMBL26134141 | 0.76 | TDP1 (0.31) | — | |
| SCHEMBL15186249 | 0.76 | — | — | |
| SCHEMBL34847 | 0.75 | — | — | |
| SCHEMBL10369750 | 0.75 | KDM4E (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759588-A | A kind of phenyl (base of pyrazolo [1,5 a] pyridine 3) ketone derivatives | 江苏新元素医药科技有限公司 | 2018-03-06 | — | — | CN | claimed |
| EP-3867248-B1 | PYRAZOLE DERIVATIVES AS H4 ANTAGONIST COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2025-12-10 | — | — | EP | disclosed |
| US-20250115587-A1 | PYRAZOLE DERIVATIVES AS H4 ANTAGONIST COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2025-04-10 | — | — | US | disclosed |
| US-12234227-B2 | Pyrazole derivatives as H4 antagonist compounds | NXERA PHARMA UK LIMITED (GB) | 2025-02-25 | — | — | US | disclosed |
| WO-2024076670-A2 | TETHERED HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| WO-2023196283-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| US-11691963-B2 | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors | AJAX THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-20230192667-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | INSILICO MEDICINE IP LIMITED (HK) | 2023-06-22 | — | — | US | disclosed |
| US-20220411403-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. | 2022-12-29 | — | — | US | disclosed |
| WO-2007099323-A2 | QUINOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-09-07 | — | — | WO | disclosed |
| CN-1154637-C | Method for producing substituted pyrazoles | �����ɷ� | 2004-06-23 | — | — | CN | disclosed |
| EP-1021416-B1 | METHOD FOR PRODUCING SUBSTITUTED PYRAZOLES | BASF AG (DE) | 2004-05-19 | — | — | EP | disclosed |
| EP-1320527-A1 | METHOD FOR PRODUCING 1 SUBSTITUTED 5-CHLORO-4 METHYL PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002026715-A1 | METHOD FOR PRODUCING 1 SUBSTITUTED 5-CHLORO-4 METHYL PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-04 | — | — | WO | disclosed |
| US-6229022-B1 | REACTING CARBONYL COMPOUNDS WITH HYDRAZINE, ITS HYDRATE OR SALTS IN THE PRESENCE OF SULFURIC ACID AND IODINE OR AN IODINE LIBERATING COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-08 | — | — | US | disclosed |
| EP-1021416-A1 | METHOD FOR PRODUCING SUBSTITUTED PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-26 | — | — | EP | disclosed |
| CN-1261351-A | Process for preparing substituted pyrazoles | BASF AG (DE) | 2000-07-26 | — | — | CN | disclosed |
| WO-1998058914-A1 | METHOD FOR PRODUCING SUBSTITUTED PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-30 | — | — | WO | disclosed |
| EP-0366329-A1 | Halogeno-4-methylpyrazoles and process for preparing the same | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1990-05-02 | — | — | EP | disclosed |