Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.86 |
| ▸ | MEN1 | O00255 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | PKM | P14618 | 2/20 | 0.77 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.71 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.65 |
| ▸ | PIM1 | P11309 | 1/20 | 0.65 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.65 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.65 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.65 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12700422 | 0.96 | DHODH (0.81) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL414754 | 0.96 | MEN1 (0.83) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL31053873 | 0.96 | MEN1 (0.83) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL16404480 | 0.94 | DHODH (0.78) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL4670044 | 0.94 | DHODH (0.78) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL8439303 | 0.94 | MEN1 (0.80) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL5931215 | 0.93 | DHODH (0.76) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL14075233 | 0.93 | DHODH (1.00) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL15183709 | 0.92 | KMT2A (0.77) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL14855554 | 0.92 | KMT2A (0.77) | DHODHMEN1KMT2APKMKCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332528-A1 | Substituted aromatic dicarbonic acid amides as medicaments | Grünenthal GmbH (DE) | 2011-06-15 | — | — | EP | claimed |
| WO-1995017321-A1 | AIRBAG CONTAINING LIQUID CRYSTALLINE POLYMER BLEND | AKZO NOBEL N.V. (NL) | 1995-06-29 | — | — | WO | claimed |
| WO-1994011417-A1 | THERMOTROPIC LIQUID CRYSTALLINE POLYAMIDE | AKZO NOBEL INC. (US) | 1994-05-26 | — | — | WO | claimed |
| US-5286838-A | Copolymer of thermoplastic aliphatic polyamide and mesogen with ortho-and/or meta-linked aromatic groups | AKZO N.V. (NL) | 1994-02-15 | — | — | US | claimed |
| EP-3056488-A1 | BISBENZOXAZINONE COMPOUND | Teijin Chemicals, Ltd. (JP) | 2016-08-17 | — | — | EP | disclosed |
| EP-2505585-B1 | BIS-BENZOXAZINONE COMPOUND | TEIJIN CHEMICALS LTD (JP) | 2016-08-03 | — | — | EP | disclosed |
| US-20120252941-A1 | BISBENZOXAZINONE COMPOUND | TEIJIN CHEMICALS, LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| EP-2332528-A1 | Substituted aromatic dicarbonic acid amides as medicaments | Grünenthal GmbH (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-1994011417-A1 | THERMOTROPIC LIQUID CRYSTALLINE POLYAMIDE | AKZO NOBEL INC. (US) | 1994-05-26 | — | — | WO | disclosed |
| US-5286838-A | Copolymer of thermoplastic aliphatic polyamide and mesogen with ortho-and/or meta-linked aromatic groups | AKZO N.V. (NL) | 1994-02-15 | — | — | US | disclosed |
| EP-0383941-B1 | ULTRAVIOLET ABSORBING COSMETIC | TEIJIN LTD (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5234681-A | A phenylene-, naphthylene- or biphenylenebis(3,1-benzoxazin-4-one; sunscreen agents; colorless, odorless and nonirritating; durability | TEIJIN LIMITED (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0383941-A1 | ULTRAVIOLET ABSORBING COSMETIC | TEIJIN LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252941-A1 | BISBENZOXAZINONE COMPOUND | RPS4Y1, RPS4X, H1-4 | DHODH 2402/4885MEN1 4533/4885KMT2A 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.