Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PAM | P19021 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844549 | 1.00 | DGKA (0.61) | DGKALMNATSHRALDH1A1PAM | |
| SCHEMBL177409 | 1.00 | DGKA (0.61) | DGKALMNATSHRALDH1A1PAM | |
| SCHEMBL7647987 | 1.00 | DGKA (0.61) | DGKALMNATSHRALDH1A1PAM | |
| SCHEMBL10642835 | 1.00 | DGKA (0.61) | DGKALMNATSHRALDH1A1PAM | |
| SCHEMBL539005 | 1.00 | DGKA (0.61) | DGKALMNATSHRALDH1A1PAM | |
| SCHEMBL926254 | 1.00 | DGKA (0.61) | DGKALMNATSHRALDH1A1PAM | |
| SCHEMBL4152672 | 1.00 | DGKA (0.61) | DGKALMNATSHRALDH1A1PAM | |
| SCHEMBL2189614 | 1.00 | DGKA (0.61) | DGKALMNATSHRALDH1A1PAM | |
| SCHEMBL7260301 | 1.00 | DGKA (0.61) | DGKALMNATSHRALDH1A1PAM | |
| SCHEMBL2222481 | 1.00 | DGKA (0.61) | DGKALMNATSHRALDH1A1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707364-B1 | PROCESS FOR THE MANUFACTURE OF DABIGATRAN ETEXILATE AND INTERMEDIATES THEREOF | EGIS GYÓGYSZERGYÁR ZRT (HU) | 2016-08-24 | — | — | EP | claimed |
| US-9260421-B2 | Pharmaceutical intermediates and process for the preparation thereof | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2016-02-16 | — | — | US | claimed |
| US-20140155614-A1 | PHARMACEUTICAL INTERMEDIATES AND PROCESS FOR THE PREPARATION THEREOF | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2014-06-05 | — | — | US | claimed |
| EP-2707364-A1 | PROCESS FOR THE MANUFACTURE OF DABIGATRAN ETEXILATE AND INTERMEDIATES THEREOF | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársaság (HU) | 2014-03-19 | — | — | EP | claimed |
| WO-2013024384-A1 | IMPROVED PROCESS FOR PREPARATION OF DABIGATRAN ETEXILATE AND ITS NOVEL INTERMEDIATE | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2013-02-21 | — | — | WO | claimed |
| WO-2012153158-A1 | PROCESS FOR THE MANUFACTURE OF DABIGATRAN ETEXILATE AND INTERMEDIATES THEREOF | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársaság (HU) | 2012-11-15 | — | — | WO | claimed |
| EP-2262771-A1 | A METHOD FOR THE PREPARATION OF DABIGATRAN | Zentiva, K.S. (CZ) | 2010-12-22 | — | — | EP | claimed |
| WO-2009111997-A1 | A METHOD FOR THE PREPARATION OF DABIGATRAN | ZENTIVA, K.S. (CZ) | 2009-09-17 | — | — | WO | claimed |
| CN-112144141-B | Copolymerized flame-retardant polyamide fiber and preparation method thereof | 东华大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-112225892-B | Copolymerization flame-retardant polyamide and preparation method thereof | 东华大学 | 2021-10-08 | — | — | CN | disclosed |
| CN-109432508-B | Decalcified bone matrix material with bone growth promoting and antibacterial functions as well as preparation method and application thereof | 中国人民解放军总医院第一附属医院 | 2021-05-28 | — | — | CN | disclosed |
| WO-2021037362-A1 | OPTIMIZED ANALYTE DERIVATIZATION FOR SYNERGISTIC APPLICATION WITH CRYSTAL SPONGE METHOD | MERCK PATENT GMBH (DE) | 2021-03-04 | — | — | WO | disclosed |
| CN-112225892-A | Copolymerization flame-retardant polyamide and preparation method thereof | 东华大学 | 2021-01-15 | — | — | CN | disclosed |
| CN-112144141-A | Copolymerized flame-retardant polyamide fiber and preparation method thereof | 东华大学 | 2020-12-29 | — | — | CN | disclosed |
| WO-2011075684-A1 | PRODRUGS OF INHIBITORS OF PLASMA KALLIKREIN | ACTIVESITE PHARMACEUTICALS, INC. (US) | 2011-06-23 | — | — | WO | disclosed |
| EP-2262771-A1 | A METHOD FOR THE PREPARATION OF DABIGATRAN | Zentiva, K.S. (CZ) | 2010-12-22 | — | — | EP | disclosed |
| WO-2010045900-A1 | A METHOD FOR THE PREPARATION OF DABIGATRAN AND ITS INTERMEDIATES | ZENTIVA, K.S. (CZ) | 2010-04-29 | — | — | WO | disclosed |
| WO-2009111997-A1 | A METHOD FOR THE PREPARATION OF DABIGATRAN | ZENTIVA, K.S. (CZ) | 2009-09-17 | — | — | WO | disclosed |
| EP-1968949-A1 | IMPROVED PROCESS FOR THE PREPARATION OF THE SALTS OF 4-(BENZIMIDAZOLYLMETHYLAMINO)-BENZAMIDES | Boehringer Ingelheim International GmbH (DE) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007071743-A1 | IMPROVED PROCESS FOR THE PREPARATION OF THE SALTS OF 4-(BENZIMIDAZOLYLMETHYLAMINO)-BENZAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155614-A1 | PHARMACEUTICAL INTERMEDIATES AND PROCESS FOR THE PREPARATION THEREOF | TFPI, VKORC1, VKORC1L1 | DGKA 1828/4885LMNA 2007/4885TSHR 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.