SCHEMBL20291332

SCHEMBL20291332

c1ccc(-c2ccc(-c3ccc4c5ccccc5n(-c5cccc(-c6cccc(-c7nc(-c8ccccc8)nc(-c8cccc9oc%10ccccc%10c89)n7)c6)c5)c4c3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PLA2G2A P14555 2/20 0.33
PLA2G4A P47712 2/20 0.33
HPSE Q9Y251 2/20 0.33
TP53 P04637 1/20 0.32
PLA2G10 O15496 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20290898 1.00 PDE10A (0.34) PDE10AKDM4EATML3MBTL1PLA2G2A
SCHEMBL20291225 1.00 PDE10A (0.34) PDE10AKDM4EATML3MBTL1PLA2G2A
SCHEMBL20291270 0.99 PDE10A (0.34) PDE10AKDM4EATML3MBTL1PLA2G2A
SCHEMBL20290670 0.99 PDE10A (0.34) PDE10AKDM4EATML3MBTL1PLA2G2A
SCHEMBL20291025 0.99 PDE10A (0.35) PDE10AKDM4EATML3MBTL1PLA2G2A
SCHEMBL20290930 0.99 PDE10A (0.35) PDE10AKDM4EATML3MBTL1PLA2G2A
SCHEMBL26080575 0.97 KDM4E (0.38) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL24361762 0.96 PDE10A (0.33) PDE10AKDM4EATML3MBTL1PLA2G2A
SCHEMBL23558076 0.96 PDE10A (0.34) PDE10AKDM4EATML3MBTL1PLA2G2A
SCHEMBL26080596 0.96 KDM4E (0.38) KDM4EATML3MBTL1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018110958-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 2018-06-21 WO disclosed