SCHEMBL26080596

SCHEMBL26080596

c1ccc(-c2cccc(-c3cccc(-c4nc(-c5ccc6c7ccccc7n(-c7ccccc7)c6c5)nc(-c5cccc6oc7ccccc7c56)n4)c3)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PLA2G2A P14555 3/20 0.34
PLA2G4A P47712 3/20 0.34
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PLA2G10 O15496 1/20 0.33
HPSE Q9Y251 1/20 0.32
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26080575 0.99 KDM4E (0.38) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL20290898 0.96 PDE10A (0.34) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL20291332 0.96 PDE10A (0.34) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL20291225 0.96 PDE10A (0.34) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL21191834 0.96 ATM (0.37) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL19239453 0.96 KDM4E (0.35) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL27253689 0.96 KDM4E (0.35) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL21707317 0.96 KDM4E (0.40) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL20291270 0.95 PDE10A (0.34) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL20290670 0.95 PDE10A (0.34) KDM4EATML3MBTL1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312538-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312538-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CYP1B1 KDM4E 2539/4885ATM 3031/4885L3MBTL1 1591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.