Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.34 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23806102 | 1.00 | BRD4 (0.46) | BRD4CYP2C19ALDH1A1ALOX15BCA1 | |
| SCHEMBL10146103 | 0.76 | BRD4 (0.55) | BRD4ALDH1A1MEN1KMT2ACNR2 | |
| SCHEMBL19625278 | 0.75 | MEN1 (0.42) | MEN1KMT2AMAPTCNR2CNR1 | |
| SCHEMBL13618718 | 0.73 | BRD4 (0.51) | BRD4MEN1KMT2ACNR2NPC1 | |
| SCHEMBL1911776 | 0.68 | PDK2 (0.47) | CYP2C19ALDH1A1ALOX15BCA1CA2 | |
| SCHEMBL13179305 | 0.66 | CDK2 (0.39) | CYP2C19ALDH1A1ALOX15BCA1CA2 | |
| SCHEMBL24623064 | 0.66 | CYP2C19 (0.55) | CYP2C19ALDH1A1ALOX15BCA1CA2 | |
| SCHEMBL20291195 | 0.66 | BRD4 (0.50) | BRD4ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13172381 | 0.66 | PDK2 (0.45) | CYP2C19ALDH1A1ALOX15BCA1CA2 | |
| SCHEMBL20291057 | 0.66 | BRD4 (0.60) | BRD4CYP2C19ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018112037-A1 | INHIBITORS OF BROMODOMAIN-CONTAINING PROTEIN 4 (BRD4) | ZHOU JIA (US) | 2018-06-21 | — | — | WO | disclosed |