Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10146103 | 0.89 | BRD4 (0.55) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10147491 | 0.74 | BRD4 (0.53) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10147510 | 0.74 | BRD4 (0.53) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL23806102 | 0.73 | BRD4 (0.46) | BRD4MEN1KMT2ANPC1CNR2 | |
| SCHEMBL20291387 | 0.73 | BRD4 (0.46) | BRD4MEN1KMT2ANPC1CNR2 | |
| SCHEMBL352017 | 0.72 | CNR2 (0.52) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL352100 | 0.72 | BRD4 (0.48) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13618545 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL13618544 | 0.72 | MEN1 (0.45) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20291057 | 0.71 | BRD4 (0.60) | BRD4MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |