Morpholine

Morpholine

SCHEMBL2029282

C1COCCN1.NP(N)(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
KDM4E B2RXH2 1/20 0.55
GAA P10253 1/20 0.55
CYP2C9 P11712 1/20 0.55
MMP1 P03956 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33
ANPEP P15144 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL412425 0.95 MEN1 (0.55) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL28817299 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL29071034 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL29377463 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL11120537 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL20580623 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL7727917 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL29208541 0.86 MEN1 (0.58) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL28503414 0.84 MEN1 (0.55) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL28056944 0.84 MEN1 (0.55) MEN1KMT2AKDM4EGAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3700570-B1 ANTISENSE OLIGOMERS FOR TREATMENT OF NON-SENSE MEDIATED RNA DECAY BASED CONDITIONS AND DISEASES STOKE THERAPEUTICS INC (US) 2025-01-08 EP claimed
CN-117545850-A Method for ligating polypeptide and oligonucleotide 南洋理工大学 2024-02-09 CN claimed
CN-108350005-B Chiral agent for preparing homogeneous oligomer 卫材R&D管理有限公司 2024-02-06 CN claimed
CN-114746550-A Compositions and methods for modulating splicing and protein expression 斯托克制药公司 2022-07-12 CN claimed
EP-4377461-A2 STRUCTURE-BASED DESIGN OF ANTISENSE OLIGONUCLEOTIDE DRUGS The Regents of University of California (US) 2024-06-05 EP disclosed
EP-4363578-A1 METHODS OF TREATING ALZHEIMER'S DISEASE Aarhus Universitet (DK) 2024-05-08 EP disclosed
CN-117858883-A GalNAc monomer and GalNAc oligonucleotide conjugate 莱尔纳生物制药私人有限公司 2024-04-09 CN disclosed
CN-117844807-A Exon skipping compositions for the treatment of muscular dystrophy 萨勒普塔医疗公司 2024-04-09 CN disclosed
CN-117545850-A Method for ligating polypeptide and oligonucleotide 南洋理工大学 2024-02-09 CN disclosed
CN-117136235-A Compositions and methods for epigenetic editing 科络玛医药公司 2023-11-28 CN disclosed
CN-116947933-A Synthesis method of 7-denitrification-2 '-deoxidization-2' -fluoro-arabinofuranose guanine phosphoramidite monomer 南通大学 2023-10-27 CN disclosed
CN-116940845-A Method of screening for inhibitors of biomolecular interactions using phase separation as an intracellular reading 普林斯顿大学理事会 2023-10-24 CN disclosed
US-20130034846-A1 MOLECULAR BIOSENSORS CAPABLE OF SIGNAL AMPLIFICATION MEDIOMICS LLC (US) 2013-02-07 US disclosed
WO-2013016280-A2 COMPOSITIONS AND METHODS FOR SELECTING APTAMERS MEDIOMICS, LLC (US) 2013-01-31 WO disclosed
EP-2534266-A1 MOLECULAR BIOSENSORS CAPABLE OF SIGNAL AMPLIFICATION Saint Louis University (US) 2012-12-19 EP disclosed
WO-2011100561-A1 MOLECULAR BIOSENSORS CAPABLE OF SIGNAL AMPLIFICATION SAINT LOUIS UNIVERSITY (US) 2011-08-18 WO disclosed
US-20110158913-A1 Antisense and pretargeting optical imaging UNIVERSITY OF MASSACHUSETTS (US) 2011-06-30 US disclosed
US-20100047791-A1 MOLECULAR ACCESSIBILITY ASSAY NATIONAL INSTITUTES OF HEALTH 2010-02-25 US disclosed
WO-2008091541-A1 MOLECULAR ACCESSIBILITY ASSAY UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2008-07-31 WO disclosed
WO-2008088865-A2 ANTISENSE AND PRETARGETING OPTICAL IMAGING UNIVERSITY OF MASSACHUSETTS (US) 2008-07-24 WO disclosed