Morpholine

Morpholine

SCHEMBL412425

C1COCCN1.NP(=O)(O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
KDM4E B2RXH2 1/20 0.55
GAA P10253 1/20 0.55
CYP2C9 P11712 1/20 0.55
MMP1 P03956 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33
ANPEP P15144 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL2029282 0.95 MEN1 (0.55) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL20580623 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL29071034 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL29377463 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL11120537 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL28817299 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL7727917 0.89 MEN1 (0.61) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL29208541 0.86 MEN1 (0.58) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL28503414 0.84 MEN1 (0.55) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL28056944 0.84 MEN1 (0.55) MEN1KMT2AKDM4EGAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9353421-B2 Aptamers that are specific for immunoglobulin-binding cell wall proteins Helmholtz-Zentrum für Umweltforschung GmbH-UFZ (DE) 2016-05-31 US claimed
EP-3841218-B1 NUCLEIC ACID BASED DETECTION METHODS APTAMER DIAGNOSTICS LTD (GB) 2024-06-26 EP disclosed
CN-117957022-A Antisense compounds and methods for targeting CUG repeats 安卓达治疗股份有限公司 2024-04-30 CN disclosed
US-11898146-B2 Aptamers against Clostridium difficile, compositions comprising aptamers against Clostridium difficile and methods of using the same LIV PROCESS, INC. (US) 2024-02-13 US disclosed
WO-2023141386-A1 SYSTEM AND PROCESS FOR VISUALIZING TARGET MOLECULES LIV PROCESS, INC. (US) 2023-07-27 WO disclosed
US-20230228751-A1 APTAMERS AGAINST SARS-COV-2 Aptamer Diagnostics Limited (GB) 2023-07-20 US disclosed
CN-116438307-A Aptamer against SARS-CoV-2 适体诊断有限公司 2023-07-14 CN disclosed
US-20230200397-A1 METHODS OF REDUCING OR PREVENTING CLOSTRIDIOIDES DIFFICILE COLONIZATION LIV PROCESS, INC. (US) 2023-06-29 US disclosed
EP-4168551-A1 APTAMERS AGAINST SARS-COV-2 Aptamer Diagnostics Limited (GB) 2023-04-26 EP disclosed
CN-115956122-A Methods of reducing or preventing colonization by clostridium difficile 利夫加工有限公司 2023-04-11 CN disclosed
WO-2007031333-A2 IMPROVEMENTS IN OR RELATING TO AMPHOTERIC LIPOSOMES NOVOSOM AG (DE) 2007-03-22 WO disclosed
EP-1764089-A1 Serum stable liposomes comprising amphoter II lipid mixtures Novosom AG (DE) 2007-03-21 EP disclosed
EP-1764090-A1 Amphoteric liposomes for local drug applications Novosom AG (DE) 2007-03-21 EP disclosed
EP-1764091-A2 Improvements in or relating to amphoteric liposomes Novosom AG (DE) 2007-03-21 EP disclosed
US-20060216343-A1 Pharmaceutical compositions comprising an oligonucleotide as an active agent NOVOSOM AG (DE) 2006-09-28 US disclosed
US-20060159737-A1 Pharmaceutical compositions for local administration NOVOSOM AG (DE) 2006-07-20 US disclosed
WO-2006063149-A1 NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2006-06-15 WO disclosed
WO-2006053646-A2 IMPROVEMENTS IN OR RELATING TO PHARMACEUTICAL COMPOSITIONS FOR LOCAL ADMINISTRATION NOVOSOM AG (DE) 2006-05-26 WO disclosed
EP-1658839-A1 Oligonucleotide/carrier combinations targeting CD40 Novosom AG (DE) 2006-05-24 EP disclosed
WO-2006048329-A1 IMPROVEMENTS IN OR RELATING TO PHARMACEUTICAL COMPOSITIONS COMPRISING AN OLIGONUCLEOTIDE AS AN ACTIVE AGENT NOVOSOM AG (DE) 2006-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060159737-A1 Pharmaceutical compositions for local administration LIPA, GOT1, CHMP4B MEN1 912/4885KMT2A 3860/4885KDM4E 3816/4885
US-20060216343-A1 Pharmaceutical compositions comprising an oligonucleotide as an active agent CD40LG, CD40, TLR9 MEN1 1090/4885KMT2A 3179/4885KDM4E 3675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.