Quinoline

Quinoline

SCHEMBL2029469

c1c[nH]cn1.c1ccc2ncccc2c1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.63
FKBP5 Q13451 1/20 0.48
NR4A2 P43354 1/20 0.43
NPC1 O15118 2/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 1/20 0.41
CYP3A4 P08684 2/20 0.40
CASP1 P29466 2/20 0.39
HTT P42858 2/20 0.39
MEN1 O00255 1/20 0.39
CASP7 P55210 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.39
HSP90AA1 P07900 1/20 0.39
HSP90AB1 P08238 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL27877830 1.00 ALDH1A1 (0.63) ALDH1A1FKBP5NR4A2NPC1POLB
Quinoline SCHEMBL27277627 1.00 ALDH1A1 (0.63) ALDH1A1FKBP5NR4A2NPC1POLB
Quinoline SCHEMBL27685815 1.00 ALDH1A1 (0.63) ALDH1A1FKBP5NR4A2NPC1POLB
Quinoline SCHEMBL28232319 0.98 ALDH1A1 (0.61) ALDH1A1FKBP5NR4A2NPC1POLB
Quinoline SCHEMBL28126307 0.98 ALDH1A1 (0.61) ALDH1A1FKBP5NR4A2NPC1POLB
Quinoline SCHEMBL27929361 0.98 ALDH1A1 (0.61) ALDH1A1FKBP5NR4A2NPC1POLB
Quinoline SCHEMBL27268450 0.98 ALDH1A1 (0.61) ALDH1A1FKBP5NR4A2NPC1POLB
Quinoline SCHEMBL27750058 0.98 ALDH1A1 (0.61) ALDH1A1FKBP5NR4A2NPC1POLB
Quinoline SCHEMBL27593554 0.93 ALDH1A1 (0.55) ALDH1A1FKBP5NR4A2NPC1POLB
Quinoline SCHEMBL28146082 0.93 ALDH1A1 (0.55) ALDH1A1FKBP5NR4A2NPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115192721-A Bladder perfusion medicine compound preparation and preparation method and application thereof 苏州百迈生物医药有限公司 2022-10-18 CN claimed
CN-110167598-A The multiarm polymers conjugate and relevant immunotherapy method of TLR agonist compound 尼克塔治疗公司 2019-08-23 CN claimed
CN-110129121-A Antirust corrosion-proof cutting fluid and preparation method thereof 黄智翔 2019-08-16 CN claimed
CN-110121335-A Drug delivery composition and application thereof 达纳-法伯癌症研究所股份有限公司 2019-08-13 CN claimed
CN-110054886-A A kind of water-resistant solution compound polyurethane material, preparation method and the application in waterproof cable product 扬州亚光电缆有限公司 2019-07-26 CN claimed
CN-110042398-A Imidazoline high temperature resistant corrosion inhibitor and preparation method thereof 中国石油化工股份有限公司 2019-07-23 CN claimed
CN-109929170-A A kind of polyethylene foamed composite material, preparation method and the application in low-and high-frequency cable product 扬州亚光电缆有限公司 2019-06-25 CN claimed
CN-109890417-A The treatment of cancer and/or prophylactic compositions 东丽株式会社 2019-06-14 CN claimed
CN-106047326-B CO suitable for high-salinity and high-barium-strontium environment2Corrosion and scale inhibitor 中国石油天然气股份有限公司 2019-06-11 CN claimed
CN-106978746-B A kind of ink-jet cloth printing technique 泉州市众科专利技术标准化研究院有限责任公司 2019-05-17 CN claimed
CN-1045109-C Concentrated fabric softener compositions containing biodegradable fabric softeners PROCTER & GAMBLE (US) 1999-09-15 CN claimed
CN-1215310-A Method of killing or inhibiting microbial cells NOVO NORDISK AS (DK) 1999-04-28 CN claimed
CN-2289514-Y Cleaning antifogging towel ZHU ZENGXI (CN) 1998-09-02 CN claimed
CN-1181035-A Shaving apparatus GILLETTE CO (US) 1998-05-06 CN claimed
CN-1167457-A Skin contact member GILLETTE CO (US) 1997-12-10 CN claimed
CN-1146172-A Shaving system GILLETTE CO (US) 1997-03-26 CN claimed
CN-1082101-A The concentrated fabric softener compositions that contains biodegradable fabric softener PROCTER & GAMBLE (US) 1994-02-16 CN claimed
CN-1075501-A The detergent composition of dye transfer when suppressing washing PROCTER & GAMBLE (US) 1993-08-25 CN claimed
CN-1060241-A Razors GILLETTE CO (US) 1992-04-15 CN claimed
CN-1060245-A Razors GILLETTE CO (US) 1992-04-15 CN claimed