SCHEMBL202952

SCHEMBL202952

CNC(=O)n1c(NC(=O)OC)nc2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.68
TSHR P16473 2/20 0.68
L3MBTL1 Q9Y468 1/20 0.47
RAB9A P51151 5/20 0.45
NPC1 O15118 3/20 0.45
POLB P06746 2/20 0.44
KDM4E B2RXH2 5/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 2/20 0.41
ASAH1 Q13510 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
HTT P42858 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CNR2 P34972 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27197724 0.87 TSHR (0.60) ALDH1A1TSHRL3MBTL1RAB9ANPC1
SCHEMBL202762 0.87 ALDH1A1 (0.54) ALDH1A1TSHRL3MBTL1RAB9ANPC1
SCHEMBL9578721 0.86 ALDH1A1 (0.65) ALDH1A1TSHRL3MBTL1RAB9ANPC1
SCHEMBL26619060 0.86 TSHR (0.51) ALDH1A1TSHRL3MBTL1RAB9ANPC1
SCHEMBL11177029 0.86 TSHR (0.64) ALDH1A1TSHRL3MBTL1RAB9ANPC1
SCHEMBL9578798 0.85 TSHR (0.78) ALDH1A1TSHRL3MBTL1RAB9ANPC1
SCHEMBL6184331 0.85 ALDH1A1 (0.64) ALDH1A1TSHRL3MBTL1RAB9ANPC1
SCHEMBL11833650 0.84 ALDH1A1 (0.62) ALDH1A1TSHRL3MBTL1RAB9ANPC1
SCHEMBL205803 0.83 TSHR (0.87) ALDH1A1TSHRL3MBTL1RAB9APOLB
SCHEMBL203792 0.83 ALDH1A1 (0.49) ALDH1A1TSHRRAB9ANPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4857541-A APPLYING TO BENOMYL RESISTANT FUNGI CANADIAN PATENTS AND DEVELOPMENT LIMITED/SOCIETE CANADIENNE DES BREVETS ET D'EXPLOITATION LIMITEE (CA) 1989-08-15 US claimed
EP-3746505-B1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW SILICONES CORP (US) 2024-06-26 EP disclosed
EP-3906245-B1 MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS DOW SILICONES CORP (US) 2024-05-29 EP disclosed
US-20240124709-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW GLOBAL TECHNOLOGIES LLC 2024-04-18 US disclosed
EP-3645640-B1 SILICONE-POLYETHER COPOLYMER, METHOD OF PREPARING SAME, AND SEALANT COMPRISING SAME DOW SILICONES CORP (US) 2024-03-06 EP disclosed
US-11884821-B2 Composition, polymer composite article formed therewith, and method of preparing same DOW SILICONES CORPORATION (US) 2024-01-30 US disclosed
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof DOW SILICONES CORPORATION (US) 2023-11-21 US disclosed
US-11807775-B2 Silicone-organic copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-11-07 US disclosed
CN-116874967-A Composition, polymer composite article formed therewith, and method of making the same 美国陶氏有机硅公司 2023-10-13 CN disclosed
US-11760841-B2 Silicone-polycarbonate copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-09-19 US disclosed
WO-2006106362-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 WO disclosed
WO-2006107762-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 WO disclosed
WO-2006106095-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 WO disclosed
EP-0585587-B1 Fungiresistant polyorganosiloxane composition TOSHIBA SILICONE (JP) 1997-05-21 EP disclosed
US-5378406-A Benzimidazolylcarbamate, pyridyl oxide zinc salt TOSHIBA SILICONE CO., LTD. (JP) 1995-01-03 US disclosed
EP-0585587-A1 Fungiresistant polyorganosiloxane composition TOSHIBA SILICONE CO., LTD. (JP) 1994-03-09 EP disclosed
EP-0256789-B1 SUBSTITUTED BENZIMIDAZOLE FUNGICIDE HER MAJESTY IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF AGRICULTURE (CA) 1993-05-05 EP disclosed
EP-0429006-A1 Method for the treatment of straw as a substrate for the cultivation of mushrooms Hüttermann, Aloys, Prof. Dr. (DE) 1991-05-29 EP disclosed
US-4857541-A APPLYING TO BENOMYL RESISTANT FUNGI CANADIAN PATENTS AND DEVELOPMENT LIMITED/SOCIETE CANADIENNE DES BREVETS ET D'EXPLOITATION LIMITEE (CA) 1989-08-15 US disclosed
EP-0256789-A1 Substituted benzimidazole fungicide HER MAJESTY IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF AGRICULTURE (CA) 1988-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof BRS3, OXSR1, OXER1 ALDH1A1 3354/4885TSHR 566/4885L3MBTL1 3456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.