Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27491873 | 1.00 | — | — | |
| Propionic Acid SCHEMBL7859381 | 0.89 | FFAR3 (0.53) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Methyl Alcohol SCHEMBL27815279 | 0.88 | — | — | |
| SCHEMBL48388 | 0.87 | — | — | |
| SCHEMBL28320955 | 0.87 | TSHR (0.38) | TSHRCASP1 | |
| Propionic Acid SCHEMBL29137673 | 0.87 | FFAR3 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Benzene SCHEMBL28293157 | 0.85 | GABRA1 (0.36) | TSHRCASP1 | |
| Glycine SCHEMBL27804687 | 0.85 | GLRA1 (0.48) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propiolic Acid SCHEMBL31195335 | 0.85 | — | — | |
| SCHEMBL23247165 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685805-B2 | Aqueous dispersion of polyurethane | COVESTRO DEUTSCHLAND AG (DE) | 2023-06-27 | — | — | US | disclosed |
| US-20210130532-A1 | AN AQUEOUS DISPERSION OF POLYURETHANE | COVESTRO DEUTSCHLAND AG (DE) | 2021-05-06 | — | — | US | disclosed |
| EP-3555161-A1 | AN AQUEOUS DISPERSION OF POLYURETHANE | Covestro Deutschland AG (DE) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018114838-A1 | AN AQUEOUS DISPERSION OF POLYURETHANE | COVESTRO DEUTSCHLAND AG (DE) | 2018-06-28 | — | — | WO | disclosed |