Neltenexine

Neltenexine

SCHEMBL20299

O=C(Nc1c(Br)cc(Br)cc1CN[C@H]1CC[C@H](O)CC1)c1cccs1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.51
CYP2D6 P10635 2/20 0.51
LMNA P02545 2/20 0.51
GBA1 P04062 1/20 0.51
CNR1 P21554 1/20 0.51
TBXA2R P21731 1/20 0.51
HRH2 P25021 1/20 0.51
SLC6A4 P31645 1/20 0.51
KCNH2 Q12809 1/20 0.51
HIF1A Q16665 1/20 0.51
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALOX15 P16050 1/20 0.50
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Neltenexine SCHEMBL10646479 1.00 CYP1A2 (0.51) CYP1A2CYP2D6LMNAGBA1CNR1
Neltenexine SCHEMBL30712623 1.00 CYP1A2 (0.51) CYP1A2CYP2D6LMNAGBA1CNR1
Neltenexine SCHEMBL15673426 0.99 CYP3A4 (0.52) CYP1A2CYP2D6LMNAGBA1CNR1
Neltenexine SCHEMBL10650927 0.99 CYP3A4 (0.52) CYP1A2CYP2D6LMNAGBA1CNR1
Neltenexine SCHEMBL13723560 0.87 LMNA (0.39) CYP1A2CYP2D6LMNAGBA1CNR1
SCHEMBL9292739 0.83 LMNA (0.55) CYP1A2CYP2D6LMNAGBA1CNR1
Hydrochloric Acid SCHEMBL9293916 0.82 CYP3A4 (0.56) CYP1A2CYP2D6LMNAGBA1CNR1
SCHEMBL16709538 0.77 LMNA (0.53) CYP1A2CYP2D6LMNAGBA1CNR1
SCHEMBL10646050 0.76 GRIN2D (0.41) CYP1A2CYP2D6LMNACYP3A4TSHR
SCHEMBL28774653 0.75 LMNA (0.56) CYP1A2CYP2D6LMNAGBA1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 US claimed
EP-4510999-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS Bristol-Myers Squibb Company (US) 2025-02-26 EP claimed
US-20240165020-A1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-05-23 US claimed
EP-4360653-A2 LIQUISOFT CAPSULES Patheon Softgels Inc. (US) 2024-05-01 EP claimed
US-11872307-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2024-01-16 US claimed
EP-3682872-B1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-01-03 EP claimed
WO-2023205619-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-10-26 WO claimed
US-20230118307-A1 THERAPEUTIC USE OF LONG-ACTING CONJUGATE OF TRIPLE AGONIST HAVING ACTIVITIES TO ALL OF GLUCAGON/GLP-1/GIP RECEPTORS FOR LUNG DISEASE HANMI PHARM. CO., LTD. (KR) 2023-04-20 US claimed
EP-4104849-A1 THERAPEUTIC USE OF LONG-ACTING CONJUGATE OF TRIPLE AGONIST HAVING ACTIVITY WITH RESPECT TO ALL OF GLUCAGON AND GLP-1 AND GIP RECEPTORS AGAINST LUNG DISEASE Hanmi Pharm. Co., Ltd. (KR) 2022-12-21 EP claimed
WO-2012069175-A1 NEW PYRAZOLE DERIVATIVES HAVING CRTH2 ANTAGONISTIC BEHAVIOUR ALMIRALL, S.A. (ES) 2012-05-31 WO claimed
EP-2457900-A1 New pyrazole derivatives having CRTh2 antagonistic behaviour Almirall, S.A. (ES) 2012-05-30 EP claimed
WO-2012025761-A1 THEOBROMINE IN COMBINATION WITH AN EXPECTORANT OR A MUCOLYTIC FOR USE IN THERAPY BIOCOPEA LIMITED (GB) 2012-03-01 WO claimed
CN-101835749-A The indoles that replaces AUSPEX PHARAMACEUTICALS INC 2010-09-15 CN claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230118307-A1 THERAPEUTIC USE OF LONG-ACTING CONJUGATE OF TRIPLE AGONIST HAVING ACTIVITIES TO ALL OF GLUCAGON/GLP-1/GIP RECEPTORS FOR LUNG DISEASE GIPR, GLP1R, GCGR CYP1A2 4838/4885CYP2D6 4765/4885LMNA 3735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.