⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31078352 | 0.72 | — | — | |
| SCHEMBL1631040 | 0.72 | — | — | |
| SCHEMBL901700 | 0.68 | — | — | |
| SCHEMBL20302246 | 0.68 | — | — | |
| SCHEMBL2283138 | 0.66 | — | — | |
| SCHEMBL31438618 | 0.66 | — | — | |
| SCHEMBL14072752 | 0.66 | — | — | |
| SCHEMBL9496465 | 0.66 | — | — | |
| SCHEMBL14709145 | 0.66 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL5414363 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304565-A1 | NOVEL BENZOFURAN, BENZOTHIOPHENE, AND INDOLE ANALOGS THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE | Oligomerix Inc. (US) | 2025-10-02 | — | — | US | disclosed |
| EP-3562483-B1 | NOVEL BENZOFURAN, BENZOTHIOPHENE, AND INDOLE ANALOGS THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE | OLIGOMERIX INC (US) | 2025-09-03 | — | — | EP | disclosed |
| US-12331043-B2 | Benzofuran, benzothiophene, and indole analogs that inhibit the formation of tau oligomers and their method of use | OLIGOMERIX, INC. (US) | 2025-06-17 | — | — | US | disclosed |
| US-20240158379-A1 | NOVEL BENZOFURAN, BENZOTHIOPHENE, AND INDOLE ANALOGS THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE | OLIGOMERIX, INC. | 2024-05-16 | — | — | US | disclosed |
| US-11306075-B2 | Benzofuran, benzothiophene, and indole analogs that inhibit the formation of tau oligomers and their method of use | OLIGOMERIX, INC. (US) | 2022-04-19 | — | — | US | disclosed |
| US-20210130335-A1 | NOVEL BENZOFURAN, BENZOTHIOPHENE, AND INDOLE ANALOGS THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE | OLIGOMERIX, INC. | 2021-05-06 | — | — | US | disclosed |
| EP-3562483-A2 | NOVEL BENZOFURAN, BENZOTHIOPHENE, AND INDOLE ANALOGS THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE | Oligomerix, Inc. (US) | 2019-11-06 | — | — | EP | disclosed |
| WO-2018118782-A2 | NOVEL BENZOFURAN, BENZOTHIOPHENE, AND INDOLE ANALOGS THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE | OLIGOMERIX, INC. (US) | 2018-06-28 | — | — | WO | disclosed |