⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542040 | 0.80 | — | — | |
| SCHEMBL8671567 | 0.78 | MMP8 (0.46) | — | |
| SCHEMBL5543296 | 0.77 | MMP8 (0.39) | — | |
| SCHEMBL190205 | 0.76 | — | — | |
| SCHEMBL5540521 | 0.75 | MMP8 (0.38) | — | |
| SCHEMBL7012372 | 0.74 | — | — | |
| SCHEMBL256014 | 0.74 | — | — | |
| SCHEMBL1372325 | 0.74 | — | — | |
| SCHEMBL282133 | 0.74 | — | — | |
| SCHEMBL353636 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104203928-B | Triazineon compounds and T-shaped calcium channel blocker | 日产化学工业株式会社 | 2017-06-06 | — | — | CN | disclosed |
| US-8614217-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2013-12-24 | — | — | US | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-20110201613-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-08-18 | — | — | US | disclosed |
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-100366624-C | 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds | OTSUKA PHARMA CO LTD (JP) | 2008-02-06 | — | — | CN | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| CN-1086704-C | Compound having antihypertensive, cardioprotective, anti-ischemic and antilipolytic functions | AVENTIS PHARMA INC (US) | 2002-06-26 | — | — | CN | disclosed |
| CN-1148811-A | Compound having antihypertensive, cardioprotective, anti-ischemic and antilipolytic functions | RHONE POULENC RORER PHARMA (US) | 1997-04-30 | — | — | CN | disclosed |
| EP-0034778-B1 | HETERO-IMINO-PROSTACYCLINS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-04-25 | — | — | EP | disclosed |
| US-4371542-A | Hetero-imino-prostacyclins | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-01 | — | — | US | disclosed |
| EP-0034778-A1 | Hetero-imino-prostacyclins and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-02 | — | — | EP | disclosed |
| US-4053478-A | ARTERIOSCLEROSIS, THROMBOSIS, HYPERTENSION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1977-10-11 | — | — | US | disclosed |
| US-4012412-A | USEFUL IN THE TREATMENT OF HYPERTENSION, ARTERIOSCLEROSIS, AND THROMBOSIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1977-03-15 | — | — | US | disclosed |