Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632732 | 0.85 | CYP1A2 (0.50) | ACHEIDO1MAPTL3MBTL1NPC1 | |
| SCHEMBL16632544 | 0.84 | CA12 (0.54) | ACHEKMT2AMAPTL3MBTL1HPGD | |
| SCHEMBL22131477 | 0.81 | SLC6A4 (0.55) | IDO1MAPTL3MBTL1HPGDESRRA | |
| SCHEMBL16640617 | 0.81 | AR (0.59) | ACHEESRRAAR | |
| SCHEMBL7457103 | 0.78 | HTR1B (0.52) | KMT2AMAPTL3MBTL1HPGDRAB9A | |
| SCHEMBL11894615 | 0.78 | ESRRA (0.53) | KMT2AIDO1MAPTL3MBTL1NPC1 | |
| SCHEMBL13871406 | 0.77 | CYP1A2 (0.61) | ACHEIDO1HPGDESRRACYP1A2 | |
| SCHEMBL29367279 | 0.76 | MAPT (0.61) | ACHEKMT2AIDO1MAPTL3MBTL1 | |
| SCHEMBL30373629 | 0.76 | MAPT (0.61) | ACHEKMT2AIDO1MAPTL3MBTL1 | |
| SCHEMBL151449 | 0.76 | MAPT (0.61) | ACHEKMT2AIDO1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252033-B1 | TWO-STAGE SYNTHESIS OF N BIARYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2018-06-27 | — | — | EP | disclosed |