Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29577853 | 0.97 | HTR1B (0.54) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| SCHEMBL442767 | 0.97 | HTR1B (0.54) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| Methane SCHEMBL10959030 | 0.95 | HTR1B (0.52) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| Lithium SCHEMBL6571336 | 0.95 | HTR1B (0.52) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| Ethylene SCHEMBL4726812 | 0.92 | HTR1B (0.50) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| Ethane SCHEMBL10636467 | 0.92 | HTR1B (0.50) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| SCHEMBL16632544 | 0.89 | CA12 (0.54) | HTR1BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10540676 | 0.88 | ALDH1A1 (0.51) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| SCHEMBL441360 | 0.86 | HPRT1 (0.61) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| Ethylene Glycol SCHEMBL8646862 | 0.86 | HTR1B (0.54) | HTR1BALDH1A1KDM4ETDP1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966436-B1 | ARYL SULFONAMIDES AND ANALOGUES THEREOF AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | BAYER AG (DE) | 2002-12-11 | — | — | EP | claimed |
| EP-0966436-B1 | ARYL SULFONAMIDES AND ANALOGUES THEREOF AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | BAYER AG (DE) | 2002-12-11 | — | — | EP | disclosed |
| EP-0189266-A2 | Purification of haloacetyl derivatives of aromatic hydrocarbons | THE DOW CHEMICAL COMPANY (US) | 1986-07-30 | — | — | EP | disclosed |