Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15926424 | 0.78 | KDM4E (0.43) | KDM4EHPGD | |
| SCHEMBL23783716 | 0.71 | CHEK1 (0.33) | KDM4EL3MBTL1MAPT | |
| SCHEMBL2243084 | 0.68 | CHUK (0.46) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL21077287 | 0.67 | DYRK1A (0.35) | — | |
| SCHEMBL2226563 | 0.65 | TP53 (0.55) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL24101511 | 0.65 | HTR1F (0.45) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL24101523 | 0.65 | HTR1F (0.45) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL25847146 | 0.65 | HTR1F (0.45) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL2222291 | 0.65 | SMN1; SMN2 (0.46) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL14339454 | 0.65 | MAPT (0.47) | CHUKKDM4EGABRPGABRDIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976329-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-06-27 | — | — | EP | disclosed |