Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17001719 | 1.00 | MEN1 (0.42) | MEN1TP53KMT2ACNR2MAPK1 | |
| SCHEMBL17001718 | 0.88 | L3MBTL3 (0.42) | F13A1TGM2TGM1L3MBTL3SMN1; SMN2 | |
| SCHEMBL20311070 | 0.88 | L3MBTL3 (0.42) | F13A1TGM2TGM1L3MBTL3SMN1; SMN2 | |
| SCHEMBL17001708 | 0.88 | L3MBTL3 (0.42) | F13A1TGM2TGM1L3MBTL3SMN1; SMN2 | |
| SCHEMBL17001727 | 0.78 | L3MBTL3 (0.38) | F13A1TGM2TGM1L3MBTL3SMN1; SMN2 | |
| SCHEMBL17001739 | 0.76 | TDP1 (0.46) | L3MBTL3SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL17001652 | 0.75 | NPC1 (0.43) | MEN1KMT2ACNR2L3MBTL3SMN1; SMN2 | |
| SCHEMBL18382076 | 0.75 | NPC1 (0.43) | MEN1KMT2ACNR2L3MBTL3SMN1; SMN2 | |
| SCHEMBL18382062 | 0.75 | DPP4 (0.39) | F13A1TGM2TGM1L3MBTL3SMN1; SMN2 | |
| SCHEMBL17001714 | 0.75 | DPP4 (0.39) | F13A1TGM2TGM1L3MBTL3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102568-B1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS. | HEPTARES THERAPEUTICS LTD (GB) | 2018-06-27 | — | — | EP | disclosed |