Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24585291 | 1.00 | FOLH1 (0.63) | FOLH1SLC6A3ALDH1A1CASRCYP1A2 | |
| SCHEMBL19756821 | 0.91 | FOLH1 (0.69) | FOLH1SLC6A3ALDH1A1CASRCYP1A2 | |
| SCHEMBL20312213 | 0.89 | FOLH1 (0.78) | FOLH1ALDH1A1 | |
| SCHEMBL22840014 | 0.89 | FOLH1 (0.78) | FOLH1ALDH1A1 | |
| SCHEMBL22840039 | 0.88 | FOLH1 (0.79) | FOLH1ALDH1A1FPR2 | |
| SCHEMBL22840031 | 0.88 | FOLH1 (0.79) | FOLH1SLC6A3CASR | |
| SCHEMBL20312202 | 0.88 | FOLH1 (0.79) | FOLH1SLC6A3CASR | |
| SCHEMBL20312237 | 0.88 | FOLH1 (0.79) | FOLH1ALDH1A1FPR2 | |
| SCHEMBL11977629 | 0.88 | FOLH1 (0.80) | FOLH1SLC6A3 | |
| SCHEMBL11977616 | 0.88 | FOLH1 (0.80) | FOLH1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942065-B1 | HETERODIMERS OF GLUTAMIC ACID | MOLECULAR INSIGHT PHARM INC (US) | 2018-06-27 | — | — | EP | disclosed |