Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 13/20 | 0.78 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22840014 | 1.00 | FOLH1 (0.78) | FOLH1EPHX1ALDH1A1HTTKDM4E | |
| SCHEMBL20335023 | 0.91 | FOLH1 (0.83) | FOLH1EPHX1ALDH1A1HTTKDM4E | |
| SCHEMBL20335021 | 0.91 | FOLH1 (0.83) | FOLH1EPHX1ALDH1A1HTTKDM4E | |
| SCHEMBL19756834 | 0.90 | FOLH1 (0.86) | FOLH1EPHX1ALDH1A1HTTLMNA | |
| SCHEMBL24585291 | 0.89 | FOLH1 (0.63) | FOLH1ALDH1A1 | |
| SCHEMBL22840039 | 0.89 | FOLH1 (0.79) | FOLH1ALDH1A1 | |
| SCHEMBL20312183 | 0.89 | FOLH1 (0.63) | FOLH1ALDH1A1 | |
| SCHEMBL22840031 | 0.89 | FOLH1 (0.79) | FOLH1 | |
| SCHEMBL20312202 | 0.89 | FOLH1 (0.79) | FOLH1 | |
| SCHEMBL20312237 | 0.89 | FOLH1 (0.79) | FOLH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942065-B1 | HETERODIMERS OF GLUTAMIC ACID | MOLECULAR INSIGHT PHARM INC (US) | 2018-06-27 | — | — | EP | disclosed |