Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 16/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22840006 | 1.00 | FOLH1 (0.77) | FOLH1ALDH1A1TGM2CYP2D6KCNH2 | |
| SCHEMBL22840033 | 0.89 | FOLH1 (0.76) | FOLH1ALDH1A1 | |
| SCHEMBL22839997 | 0.88 | FOLH1 (0.77) | FOLH1ALDH1A1 | |
| SCHEMBL22839976 | 0.88 | FOLH1 (0.61) | FOLH1TGM2 | |
| SCHEMBL20312089 | 0.88 | FOLH1 (0.61) | FOLH1TGM2 | |
| SCHEMBL24585283 | 0.88 | FOLH1 (0.77) | FOLH1 | |
| SCHEMBL17700969 | 0.87 | FOLH1 (1.00) | FOLH1 | |
| SCHEMBL11977594 | 0.87 | FOLH1 (1.00) | FOLH1 | |
| SCHEMBL21991730 | 0.86 | FOLH1 (0.98) | FOLH1 | |
| SCHEMBL22840029 | 0.81 | FOLH1 (0.78) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942065-B1 | HETERODIMERS OF GLUTAMIC ACID | MOLECULAR INSIGHT PHARM INC (US) | 2018-06-27 | — | — | EP | disclosed |