Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 15/20 | 0.61 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20312089 | 1.00 | FOLH1 (0.61) | FOLH1TGM2CHRM2HDAC3HDAC4 | |
| SCHEMBL22840033 | 0.89 | FOLH1 (0.76) | FOLH1 | |
| SCHEMBL22840006 | 0.88 | FOLH1 (0.77) | FOLH1TGM2 | |
| SCHEMBL22839997 | 0.88 | FOLH1 (0.77) | FOLH1CHRM2 | |
| SCHEMBL20312204 | 0.88 | FOLH1 (0.77) | FOLH1TGM2 | |
| SCHEMBL24585283 | 0.88 | FOLH1 (0.77) | FOLH1 | |
| SCHEMBL11977626 | 0.87 | FOLH1 (0.80) | FOLH1 | |
| SCHEMBL15449629 | 0.87 | FOLH1 (0.80) | FOLH1 | |
| SCHEMBL24585284 | 0.87 | FOLH1 (0.61) | FOLH1 | |
| SCHEMBL24585291 | 0.84 | FOLH1 (0.63) | FOLH1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699162-B1 | HETERODIMERS OF GLUTAMIC ACID | MOLECULAR INSIGHT PHARM INC (US) | 2022-06-29 | — | — | EP | disclosed |
| EP-3335736-B1 | HETERODIMERS OF GLUTAMIC ACID | MOLECULAR INSIGHT PHARM INC (US) | 2020-12-30 | — | — | EP | disclosed |