Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202310 | 0.90 | AR (0.45) | AR | |
| SCHEMBL2755440 | 0.88 | CYP1A2 (0.41) | AR | |
| SCHEMBL2702699 | 0.85 | MKNK2 (0.38) | AR | |
| SCHEMBL202351 | 0.85 | AR (0.48) | AR | |
| SCHEMBL203046 | 0.85 | AR (0.48) | AR | |
| SCHEMBL202414 | 0.85 | AR (0.48) | AR | |
| SCHEMBL201579 | 0.85 | AR (0.48) | AR | |
| SCHEMBL203883 | 0.82 | AR (0.47) | AR | |
| SCHEMBL13986515 | 0.81 | AR (0.41) | AR | |
| SCHEMBL201907 | 0.80 | PLA2G7 (0.42) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817292-B1 | NOVEL HETEROCYCLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-08 | — | — | EP | disclosed |
| US-8088811-B2 | Heterocycle derivatives useful as selective androgen receptor modulators (SARMs) | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-01-03 | — | — | US | disclosed |