SCHEMBL203177

SCHEMBL203177

CCCCCCCCC(CC)COC(=O)c1ccccc1C(=O)OCC(CC)CCCCCCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 1.00
PRSS2 P07478 1/20 1.00
PRSS3 P35030 1/20 1.00
ALDH1A1 P00352 11/20 0.89
CYP3A4 P08684 5/20 0.89
CA2 P00918 1/20 0.89
LMNA P02545 4/20 0.75
TSHR P16473 9/20 0.65
MAPK1 P28482 4/20 0.65
TP53 P04637 1/20 0.58
TDP1 Q9NUW8 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
HSD17B10 Q99714 3/20 0.54
KDM4E B2RXH2 1/20 0.50
POLB P06746 1/20 0.50
ATM Q13315 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3029945 1.00 PRSS1 (1.00) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL14377252 1.00 PRSS1 (1.00) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL31436407 1.00 PRSS1 (1.00) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL30532537 0.98 PRSS1 (0.97) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL28396810 0.98 PRSS1 (0.97) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL30532536 0.98 PRSS1 (0.97) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
Bis(2-Ethylhexyl) Phthalate SCHEMBL4434574 0.97 PRSS1 (0.94) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
Bis(2-Ethylhexyl) Phthalate SCHEMBL2345381 0.97 PRSS1 (0.94) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL28205289 0.96 PRSS1 (0.92) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL3772079 0.95 PRSS1 (0.90) PRSS1PRSS2PRSS3ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773192-B2 Process of preparing polyolefin with the discontinuous addition of a thermal runaway reducing agent SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-10-03 US claimed
EP-3510056-B2 PROCESS OF PREPARING POLYOLEFIN WITH THE DISCONTINUOUS ADDITION OF A THERMAL RUNAWAY REDUCING AGENT SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-07-19 EP claimed
US-11384166-B2 Process of preparing polyolefin with the discontinuous addition of a thermal runaway reducing agent SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-07-12 US claimed
US-11993672-B2 Production of high melt flow propylene-based polymer and product from same W.R. GRACE & CO.-CONN. (US) 2024-05-28 US disclosed
US-20240150503-A1 Propylene-ethylene copolymer compositions suitable for hot fill packaging of foodstuffs W.R. GRACE & CO.-CONN. (US) 2024-05-09 US disclosed
US-11905347-B2 Propylene-ethylene random copolymers with low XS/ET ratio and high MFR W.R. GRACE & CO .- CONN. (US) 2024-02-20 US disclosed
US-11873355-B2 Propylene-ethylene copolymer compositions suitable for hot fill packaging of foodstuffs W.R. GRACE & CO.-CONN. (US) 2024-01-16 US disclosed
WO-2024008770-A1 CATALYST SYSTEM FOR POLYMERIZATION OF AN OLEFIN SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-01-11 WO disclosed
CN-114341254-B Health care articles comprising random propylene-ethylene copolymers SABIC环球技术有限责任公司 2024-01-09 CN disclosed
US-11773192-B2 Process of preparing polyolefin with the discontinuous addition of a thermal runaway reducing agent SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-10-03 US disclosed
CN-107922694-B Process for producing low emission polypropylene SABIC环球技术有限责任公司 2023-08-15 CN disclosed
EP-0426140-A2 Process for the preparation of random copolymers UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1991-05-08 EP disclosed
US-4983562-A CATALYST PRECURSOR CONTAINING MAGNESIUM, TITANIUM, HALOGEN, ELECTRON DONOR AND CERIUM COMPOUND; HYDROCARBYLALUMINUM COCATALYST; SELECTIVITY CONTROL AGENT UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1991-01-08 US disclosed
EP-0361371-A2 Process for the preparation of alphaolefin polymers UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (a New York corporation) (US) 1990-04-04 EP disclosed
US-4882380-A CATALYSIS WITH TITANIUM, MAGNESIUM, AND CHLORINE PRECURSOR; ELECTRON DONOR; HYDROCARBYLALUMINUM COCATALYST, AND SELECTIVITY CONTROL AGENT; NONWHITENING UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1989-11-21 US disclosed
EP-0341724-A1 Process for the preparation of random copolymers UNION CARBIDE CORPORATION (US) 1989-11-15 EP disclosed
EP-0341723-A2 Process for the preparation of random copolymers UNION CARBIDE CORPORATION (US) 1989-11-15 EP disclosed
EP-0340688-A2 Process for the preparation of high purity alpha-olefin polymers UNION CARBIDE CORPORATION (US) 1989-11-08 EP disclosed
EP-0298453-A1 Process for the production of impact polypropylene copolymers UNION CARBIDE CORPORATION (US) 1989-01-11 EP disclosed
EP-0291958-A2 Process for producing stereoregular polymers having a narrow molecular weight distribution UNION CARBIDE CORPORATION (US) 1988-11-23 EP disclosed