SCHEMBL3029945

SCHEMBL3029945

CCCCCCC(CC)COC(=O)c1ccccc1C(=O)OCC(CC)CCCCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 1.00
PRSS2 P07478 1/20 1.00
PRSS3 P35030 1/20 1.00
ALDH1A1 P00352 11/20 0.89
CYP3A4 P08684 5/20 0.89
CA2 P00918 1/20 0.89
LMNA P02545 4/20 0.75
TSHR P16473 9/20 0.65
MAPK1 P28482 4/20 0.65
TP53 P04637 1/20 0.58
TDP1 Q9NUW8 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
HSD17B10 Q99714 3/20 0.54
KDM4E B2RXH2 1/20 0.50
POLB P06746 1/20 0.50
ATM Q13315 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14377252 1.00 PRSS1 (1.00) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL31436407 1.00 PRSS1 (1.00) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL203177 1.00 PRSS1 (1.00) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL30532537 0.98 PRSS1 (0.97) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL28396810 0.98 PRSS1 (0.97) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL30532536 0.98 PRSS1 (0.97) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
Bis(2-Ethylhexyl) Phthalate SCHEMBL4434574 0.97 PRSS1 (0.94) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
Bis(2-Ethylhexyl) Phthalate SCHEMBL2345381 0.97 PRSS1 (0.94) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL28205289 0.96 PRSS1 (0.92) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL3772079 0.95 PRSS1 (0.90) PRSS1PRSS2PRSS3ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3228667-B1 INSULATION MATERIAL KURARAY CO (JP) 2025-02-05 EP disclosed
US-20230343604-A1 SEMICONDUCTOR DEVICE AND METHOD TAIWAN SEMICONDUCTOR MFG CO LTD (TW) 2023-10-26 US disclosed
US-20230343604-A1 SEMICONDUCTOR DEVICE AND METHOD TAIWAN SEMICONDUCTOR MFG CO LTD (TW) 2023-10-26 US disclosed
US-11728181-B2 Semiconductor device and method TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2023-08-15 US disclosed
US-11728181-B2 Semiconductor device and method TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2023-08-15 US disclosed
US-10811165-B2 Insulation material KURARAY CO., LTD. (JP) 2020-10-20 US disclosed
US-20200279755-A1 Semiconductor Device and Method TAIWAN SEMICONDUCTOR MFG CO LTD (TW) 2020-09-03 US disclosed
US-20180061669-A1 Semiconductor Device and Method TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2018-03-01 US disclosed
EP-3228667-A1 INSULATION MATERIAL Kuraray Co., Ltd. (JP) 2017-10-11 EP disclosed
US-20170271042-A1 INSULATION MATERIAL KURARAY CO., LTD. (JP) 2017-09-21 US disclosed
US-8877332-B2 Use of a mixture comprising spherical metal particles and metal flakes as laser-marking or laser-weldability agents and laser markable and/or laser weldable plastic ECKART GMBH (DE) 2014-11-04 US disclosed
US-20140228135-A1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT AND CONSTANT VELOCITY JOINT KYODO YUSHI CO., LTD. (JP) 2014-08-14 US disclosed
US-8318262-B2 Use of spherical metal particles as laser-marking or laser-weldability agents, and laser-markable and/or laser-weldable plastic ECKART GMBH (DE) 2012-11-27 US disclosed
US-20100323934-A1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT AND CONSTANT VELOCITY JOINT NTN CORPORATION (JP) 2010-12-23 US disclosed
US-20100196698-A1 USE OF A MIXTURE COMPRISING SPHERICAL METAL PARTICLES AND METAL FLAKES AS LASER-MARKING OR LASER-WELDABILITY AGENTS AND LASER MARKABLE AND/OR LASER WELDABLE PLASTIC ECKART GMBH (DE) 2010-08-05 US disclosed
US-20100009171-A1 USE OF SPHERICAL METAL PARTICLES AS LASER-MARKING OR LASER-WELDABILITY AGENTS, AND LASER-MARKABLE AND/OR LASER-WELDABLE PLASTIC ECKART GMBH (DE) 2010-01-14 US disclosed