SCHEMBL20318803

SCHEMBL20318803

Cc1cc(N(C)C(=O)[C@@H]2[C@@H](Cc3ccnc(N)c3)C(=O)N2C(=O)N[C@@H](C2CCCCC2)C2CC2)ccn1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ F11 P03951 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21460408 1.00 F11 (0.67) F11
SCHEMBL21460391 0.93 F11 (0.68) F11
SCHEMBL20318759 0.93 F11 (0.68) F11
SCHEMBL20318810 0.92 F11 (0.68) F11
SCHEMBL20318863 0.92 F11 (0.68) F11
SCHEMBL20318957 0.92 F11 (0.68) F11
SCHEMBL21460422 0.92 F11 (0.68) F11
SCHEMBL20318935 0.92 F11 (0.68) F11
SCHEMBL21460404 0.90 F11 (0.67) F11
SCHEMBL20318760 0.90 F11 (0.67) F11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190315711-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS Cadrenal Therapeutics, Inc. 2019-10-17 — — US disclosed
US-20190315711-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS Cadrenal Therapeutics, Inc. 2019-10-17 — — US disclosed
WO-2018118705-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS EXITHERA PHARMACEUTICALS, INC. (US) 2018-06-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315711-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS KLK5, KLK2, KLKB1 F11 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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