Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.66 |
| ▸ | LTB4R2 | Q9NPC1 | 11/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033 | 1.00 | AGTR1 (0.66) | AGTR1LTB4R2ABCB11GP6MME | |
| SCHEMBL29561367 | 1.00 | AGTR1 (0.66) | AGTR1LTB4R2ABCB11GP6MME | |
| SCHEMBL1808771 | 1.00 | AGTR1 (0.66) | AGTR1LTB4R2ABCB11GP6MME | |
| SCHEMBL2978 | 0.93 | AGTR1 (0.57) | AGTR1LTB4R2ABCB11GP6MME | |
| SCHEMBL2979 | 0.93 | AGTR1 (0.57) | AGTR1LTB4R2ABCB11GP6MME | |
| SCHEMBL8487504 | 0.91 | AGTR1 (0.56) | AGTR1LTB4R2ABCB11GP6MME | |
| SCHEMBL2629 | 0.90 | LTB4R2 (0.54) | AGTR1LTB4R2ABCB11GP6MME | |
| SCHEMBL2628 | 0.90 | LTB4R2 (0.54) | AGTR1LTB4R2ABCB11GP6MME | |
| SCHEMBL27791229 | 0.90 | AGTR1 (0.53) | AGTR1LTB4R2ABCB11GP6MME | |
| SCHEMBL27791231 | 0.90 | AGTR1 (0.53) | AGTR1LTB4R2ABCB11GP6MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |